OR4K1

OR4K1
Identifiers
Aliases	OR4K1, OR14-19, olfactory receptor family 4 subfamily K member 1
External IDs	MGI: 3030562 HomoloGene: 74224 GeneCards: OR4K1
Gene location (Human)
Chr.	Chromosome 14 (human)[1]
End	19,936,757 bp[1]
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)[2]
End	50,380,137 bp[2]
RNA expression pattern
	Top expressed in
	gallbladder;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	transmembrane signaling receptor activity; olfactory receptor activity; signal transducer activity; G protein-coupled receptor activity;
Cellular component	membrane; integral component of membrane; plasma membrane;
Biological process	sensory perception of smell; detection of chemical stimulus involved in sensory perception of smell; signal transduction; response to stimulus; detection of chemical stimulus involved in sensory perception; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	79544
	258039
	ENSG00000155249
	ENSMUSG00000050030
	Q8NGD4
	Q7TRM6
	NM_001004063
	NM_001011809
	NP_001004063
	NP_001011809
	Wikidata
View/Edit Human	View/Edit Mouse

Olfactory receptor 4K1 is a protein that in humans is encoded by the OR4K1 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

References

GRCh38: Ensembl release 89: ENSG00000155249 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000050030 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: OR4K1 olfactory receptor, family 4, subfamily K, member 1".

Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000155249 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000050030 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: OR4K1 olfactory receptor, family 4, subfamily K, member 1".

OR4K1

See also

References

Further reading