OR4K5

Olfactory receptor 4K5 is a protein that in humans is encoded by the OR4K5 gene.[5][6]

OR4K5
Identifiers
AliasesOR4K5, OR14-16, olfactory receptor family 4 subfamily K member 5
External IDsMGI: 3030563 HomoloGene: 17167 GeneCards: OR4K5
Orthologs
SpeciesHumanMouse
Entrez

79317

258275

Ensembl

ENSG00000176281

ENSMUSG00000049011

UniProt

Q8NGD3

Q8VET4

RefSeq (mRNA)

NM_001005483

NM_146278

RefSeq (protein)

NP_001005483

NP_666390

Location (UCSC)Chr 14: 19.92 โ€“ 19.92 MbChr 14: 50.38 โ€“ 50.39 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[6]

See also

References

  1. GRCh38: Ensembl release 89: ENSG00000176281 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000049011 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Malnic B, Godfrey PA, Buck LB (Feb 2004). "The human olfactory receptor gene family". Proc Natl Acad Sci U S A. 101 (8): 2584โ€“9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
  6. "Entrez Gene: OR4K5 olfactory receptor, family 4, subfamily K, member 5".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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