OR4K5

OR4K5
Identifiers
Aliases	OR4K5, OR14-16, olfactory receptor family 4 subfamily K member 5
External IDs	MGI: 3030563 HomoloGene: 17167 GeneCards: OR4K5
Gene location (Human)
Chr.	Chromosome 14 (human)[1]
End	19,921,578 bp[1]
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)[2]
End	50,390,367 bp[2]
RNA expression pattern
	Top expressed in
	brain; ; cerebral cortex; ; multicellular organism;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; olfactory receptor activity; transmembrane signaling receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	sensory perception of smell; detection of chemical stimulus involved in sensory perception of smell; detection of chemical stimulus involved in sensory perception; signal transduction; response to stimulus; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	79317
	258275
	ENSG00000176281
	ENSMUSG00000049011
	Q8NGD3
	Q8VET4
	NM_001005483
	NM_146278
	NP_001005483
	NP_666390
	Wikidata
View/Edit Human	View/Edit Mouse

Olfactory receptor 4K5 is a protein that in humans is encoded by the OR4K5 gene.[5][6]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[6]

References

GRCh38: Ensembl release 89: ENSG00000176281 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000049011 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Malnic B, Godfrey PA, Buck LB (Feb 2004). "The human olfactory receptor gene family". Proc Natl Acad Sci U S A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
"Entrez Gene: OR4K5 olfactory receptor, family 4, subfamily K, member 5".

External links

OR4K5+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000176281 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000049011 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid14983052-5] Malnic B, Godfrey PA, Buck LB (Feb 2004). "The human olfactory receptor gene family". Proc Natl Acad Sci U S A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

[entrez-6] "Entrez Gene: OR4K5 olfactory receptor, family 4, subfamily K, member 5".

OR4K5

See also

References

Further reading

External links