OR2AK2

OR2AK2
Identifiers
Aliases	OR2AK2, OR1-47, OR2AK1P, olfactory receptor family 2 subfamily AK member 2
External IDs	MGI: 3030150 HomoloGene: 133825 GeneCards: OR2AK2
Gene location (Human)
Chr.	Chromosome 1 (human)[1]
End	247,966,386 bp[1]
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)[2]
End	58,650,497 bp[2]
RNA expression pattern
	Top expressed in
	prefrontal cortex; ; nucleus accumbens; ; hypothalamus; ; male reproductive system; ; testicle;
	Top expressed in
	secondary oocyte; ; hippocampus proper; ; gonad; ; testicle;
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; olfactory receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	sensory perception of smell; signal transduction; response to stimulus; detection of chemical stimulus involved in sensory perception of smell; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	391191
	258064
	ENSG00000187080
	ENSMUSG00000107677
	Q8NG84
	A0A0N4SVP2
	NM_001004491
	NM_001011818
	NP_001004491
	NP_001011818
	Wikidata
View/Edit Human	View/Edit Mouse

Olfactory receptor 2AK2 is a protein that in humans is encoded by the OR2AK2 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

References

GRCh38: Ensembl release 89: ENSG00000187080 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000107677 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: OR2AK2 olfactory receptor, family 2, subfamily AK, member 2".

External links

OR2AK2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000187080 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000107677 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: OR2AK2 olfactory receptor, family 2, subfamily AK, member 2".

OR2AK2

See also

References

Further reading

External links