OR2W3

OR2W3
Identifiers
Aliases	OR2W3, OR2W3P, OR2W8P, OST718, olfactory receptor family 2 subfamily W member 3
External IDs	OMIM: 616729 MGI: 3030156 HomoloGene: 19876 GeneCards: OR2W3
Gene location (Human)
Chr.	Chromosome 1 (human)[1]
End	247,896,531 bp[1]
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)[2]
End	58,560,354 bp[2]
RNA expression pattern
	Top expressed in
	blood; ; monocyte; ; cancellous bone; ; bone marrow; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; prefrontal cortex; ; tibial nerve; ; bone marrow cells; ; hypothalamus;
	Top expressed in
	bone marrow;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity; olfactory receptor activity;
Cellular component	membrane; plasma membrane; integral component of membrane;
Biological process	sensory perception of smell; signal transduction; response to stimulus; detection of chemical stimulus involved in sensory perception of smell; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	343171
	404346
	ENSG00000238243
	ENSMUSG00000063549
	Q7Z3T1
	Q5NCC8
	NM_001001957
	NM_207693
	NP_001001957
	NP_997576
	Wikidata
View/Edit Human	View/Edit Mouse

Olfactory receptor 2W3 is a protein that in humans is encoded by the OR2W3 gene.[5][6]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[6]

References

GRCh38: Ensembl release 89: ENSG00000238243 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000063549 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Malnic B, Godfrey PA, Buck LB (Feb 2004). "The human olfactory receptor gene family". Proc Natl Acad Sci U S A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
"Entrez Gene: OR2W3 olfactory receptor, family 2, subfamily W, member 3".

External links

OR2W3+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000238243 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000063549 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid14983052-5] Malnic B, Godfrey PA, Buck LB (Feb 2004). "The human olfactory receptor gene family". Proc Natl Acad Sci U S A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

[entrez-6] "Entrez Gene: OR2W3 olfactory receptor, family 2, subfamily W, member 3".

OR2W3

See also

References

Further reading

External links