OR5P3

Olfactory receptor 5P3 is a protein that in humans is encoded by the OR5P3 gene.[5]

OR5P3
Identifiers
AliasesOR5P3, JCG1, olfactory receptor family 5 subfamily P member 3
External IDsMGI: 3030342 HomoloGene: 72039 GeneCards: OR5P3
Orthologs
SpeciesHumanMouse
Entrez

120066

258769

Ensembl

ENSG00000182334
ENSG00000280808
ENSG00000278253

ENSMUSG00000063764

UniProt

Q8WZ94

Q8VG42

RefSeq (mRNA)

NM_153445

NM_146773

RefSeq (protein)

NP_703146

NP_666984

Location (UCSC)Chr 11: 7.82 – 7.83 MbChr 7: 108.23 – 108.23 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

Ligands

The OR5P3 receptor is associated with examples of ligands includes:[6][7]

  • 1-octanol
  • celery ketone
  • (-)-carvone

See also

References

  1. ENSG00000280808, ENSG00000278253 GRCh38: Ensembl release 89: ENSG00000182334, ENSG00000280808, ENSG00000278253 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000063764 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: OR5P3 olfactory receptor, family 5, subfamily P, member 3".
  6. Audouze K, Tromelin A, Le Bon AM, Belloir C, Petersen RK, Kristiansen K, et al. (2014). "Identification of odorant-receptor interactions by global mapping of the human odorome". PLOS ONE. 9 (4): e93037. Bibcode:2014PLoSO...993037A. doi:10.1371/journal.pone.0093037. PMC 3973694. PMID 24695519.
  7. Sanz G, Thomas-Danguin T, Hamdani EH, Le Poupon C, Briand L, Pernollet JC, et al. (September 2008). "Relationships between molecular structure and perceived odor quality of ligands for a human olfactory receptor". Chemical Senses. 33 (7): 639–53. doi:10.1093/chemse/bjn032. PMID 18603653.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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