OR5P3

OR5P3
Identifiers
Aliases	OR5P3, JCG1, olfactory receptor family 5 subfamily P member 3
External IDs	MGI: 3030342 HomoloGene: 72039 GeneCards: OR5P3
Gene location (Human)
Chr.	Chromosome 11 (human)[1]
End	7,830,840 bp[1]
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)[2]
End	108,230,835 bp[2]
RNA expression pattern
	Top expressed in
	skin of abdomen; ; urinary bladder;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; odorant binding; olfactory receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	sensory perception of smell; signal transduction; response to stimulus; detection of chemical stimulus involved in sensory perception of smell; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	120066
	258769
	ENSG00000182334; ENSG00000280808; ENSG00000278253
	ENSMUSG00000063764
	Q8WZ94
	Q8VG42
	NM_153445
	NM_146773
	NP_703146
	NP_666984
	Wikidata
View/Edit Human	View/Edit Mouse

Olfactory receptor 5P3 is a protein that in humans is encoded by the OR5P3 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

Ligands

The OR5P3 receptor is associated with examples of ligands includes:[6][7]

1-octanol
celery ketone
(-)-carvone

References

ENSG00000280808, ENSG00000278253 GRCh38: Ensembl release 89: ENSG00000182334, ENSG00000280808, ENSG00000278253 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000063764 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: OR5P3 olfactory receptor, family 5, subfamily P, member 3".
Audouze K, Tromelin A, Le Bon AM, Belloir C, Petersen RK, Kristiansen K, et al. (2014). "Identification of odorant-receptor interactions by global mapping of the human odorome". PLOS ONE. 9 (4): e93037. Bibcode:2014PLoSO...993037A. doi:10.1371/journal.pone.0093037. PMC 3973694. PMID 24695519.
Sanz G, Thomas-Danguin T, Hamdani EH, Le Poupon C, Briand L, Pernollet JC, et al. (September 2008). "Relationships between molecular structure and perceived odor quality of ligands for a human olfactory receptor". Chemical Senses. 33 (7): 639–53. doi:10.1093/chemse/bjn032. PMID 18603653.

External links

OR5P3+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCh38Ensembl-1] ENSG00000280808, ENSG00000278253 GRCh38: Ensembl release 89: ENSG00000182334, ENSG00000280808, ENSG00000278253 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000063764 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: OR5P3 olfactory receptor, family 5, subfamily P, member 3".

[pmid24695519-6] Audouze K, Tromelin A, Le Bon AM, Belloir C, Petersen RK, Kristiansen K, et al. (2014). "Identification of odorant-receptor interactions by global mapping of the human odorome". PLOS ONE. 9 (4): e93037. Bibcode:2014PLoSO...993037A. doi:10.1371/journal.pone.0093037. PMC 3973694. PMID 24695519.

[pmid18603653-7] Sanz G, Thomas-Danguin T, Hamdani EH, Le Poupon C, Briand L, Pernollet JC, et al. (September 2008). "Relationships between molecular structure and perceived odor quality of ligands for a human olfactory receptor". Chemical Senses. 33 (7): 639–53. doi:10.1093/chemse/bjn032. PMID 18603653.

OR5P3

Ligands

See also

References

Further reading

External links