OR52D1

Olfactory receptor 52D1 is a protein that in humans is encoded by the OR52D1 gene.[5]

OR52D1
Identifiers
AliasesOR52D1, OR11-43, olfactory receptor family 52 subfamily D member 1, olfactory receptor family 52 subfamily D member 1 (gene/pseudogene)
External IDsMGI: 3030480 HomoloGene: 17481 GeneCards: OR52D1
Orthologs
SpeciesHumanMouse
Entrez

390066

259058

Ensembl

ENSG00000181609

ENSMUSG00000073931

UniProt

Q9H346

Q8VGW2

RefSeq (mRNA)

NM_001005163

NM_147056

RefSeq (protein)

NP_001005163

NP_667267

Location (UCSC)Chr 11: 5.49 – 5.49 MbChr 7: 103.75 – 103.76 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

Ligands

Compared to other olfactory receptors such as OR1G1, OR52D1 has a more narrow/specific range of ligands.[6]

Agonists:

See also

References

  1. GRCh38: Ensembl release 89: ENSG00000181609 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000073931 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: OR52D1 olfactory receptor, family 52, subfamily D, member 1".
  6. Sanz G, Schlegel C, Pernollet JC, Briand L (January 2005). "Comparison of odorant specificity of two human olfactory receptors from different phylogenetic classes and evidence for antagonism". Chemical Senses. 30 (1): 69–80. doi:10.1093/chemse/bji002. PMID 15647465.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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