OR5I1

OR5I1
Identifiers
Aliases	OR5I1, HSOlf1, OLF1, olfactory receptor family 5 subfamily I member 1
External IDs	OMIM: 608496 MGI: 1313139 HomoloGene: 4835 GeneCards: OR5I1
Gene location (Human)
Chr.	Chromosome 11 (human)[1]
End	55,936,400 bp[1]
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)[2]
End	87,614,916 bp[2]
RNA expression pattern
	Top expressed in
	cell; ; monocyte; ; reproductive system; ; reproductive organ; ; male reproductive system; ; gonad; ; testicle;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; odorant binding; olfactory receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	sensory perception of smell; signal transduction; response to stimulus; detection of chemical stimulus involved in sensory perception of smell; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	10798
	258640
	ENSG00000167825
	ENSMUSG00000068816
	Q13606
	n/a
	NM_006637
	NM_146646
	NP_006628
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Olfactory receptor 5I1 is a protein that in humans is encoded by the OR5I1 gene.[5][6][7]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[7]

References

GRCh38: Ensembl release 89: ENSG00000167825 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000068816 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Issel-Tarver L, Rine J (Apr 1997). "The Evolution of Mammalian Olfactory Receptor Genes". Genetics. 145 (1): 185–95. doi:10.1093/genetics/145.1.185. PMC 1207777. PMID 9017400.
Buettner JA, Glusman G, Ben-Arie N, Ramos P, Lancet D, Evans GA (Dec 1998). "Organization and evolution of olfactory receptor genes on human chromosome 11". Genomics. 53 (1): 56–68. doi:10.1006/geno.1998.5422. PMID 9787077.
"Entrez Gene: OR5I1 olfactory receptor, family 5, subfamily I, member 1".

External links

OR5I1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000167825 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000068816 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9017400-5] Issel-Tarver L, Rine J (Apr 1997). "The Evolution of Mammalian Olfactory Receptor Genes". Genetics. 145 (1): 185–95. doi:10.1093/genetics/145.1.185. PMC 1207777. PMID 9017400.

[pmid9787077-6] Buettner JA, Glusman G, Ben-Arie N, Ramos P, Lancet D, Evans GA (Dec 1998). "Organization and evolution of olfactory receptor genes on human chromosome 11". Genomics. 53 (1): 56–68. doi:10.1006/geno.1998.5422. PMID 9787077.

[entrez-7] "Entrez Gene: OR5I1 olfactory receptor, family 5, subfamily I, member 1".

OR5I1

See also

References

Further reading

External links