Dipentylone

Dipentylone (also known as Dimethylpentylone) is a substituted cathinone derivative with stimulant effects,[1] which has been sold as a designer drug,[2][3] first detected in Sweden in 2014.[4]

Dipentylone
Legal status
Legal status
  • DE: NpSG (Industrial and scientific use only)
  • UK: Class B
Identifiers
IUPAC name
  • 1-(1,3-benzodioxol-5-yl)-2-(dimethylamino)pentan-1-one
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC14H19NO3
Molar mass249.310 g·mol−1
3D model (JSmol)
SMILES
  • CCCC(C(=O)C1=CC2=C(C=C1)OCO2)N(C)C
InChI
  • InChI=1S/C14H19NO3/c1-4-5-11(15(2)3)14(16)10-6-7-12-13(8-10)18-9-17-12/h6-8,11H,4-5,9H2,1-3H3
  • Key:PQTJKFUXRBKONZ-UHFFFAOYSA-N

N,N-DiMethylPentylone was first identified in toxicology samples in the USA in late 2021 and has been tracked by The Center for Forensic Science Research and Education (CFSRE) as an increasing common drug mismarketed as MDMA where Eutylone was previously commonly mismarketed as MDMA.[5]

Dimethylpentylone is not specifically listed in the United States Controlled Substance Act but would likely be considered illegal as a positional isomer of N-Ethylpentylone which is a schedule 1 substance in the United States and defined as "all isomers" within that definition.[6] [7]

Pentylone is a known metabolite of Dimethylpentylone.

See also

References

  1. Gatch MB, Shetty RA, Sumien N, Forster MJ (July 2021). "Behavioral effects of four novel synthetic cathinone analogs in rodents". Addiction Biology. 26 (4): e12987. doi:10.1111/adb.12987. PMID 33155384. S2CID 226271372.
  2. Celma A, Sancho JV, Salgueiro-González N, Castiglioni S, Zuccato E, Hernández F, Bijlsma L (September 2019). "Simultaneous determination of new psychoactive substances and illicit drugs in sewage: Potential of micro-liquid chromatography tandem mass spectrometry in wastewater-based epidemiology". Journal of Chromatography A. 1602: 300–309. doi:10.1016/j.chroma.2019.05.051. hdl:10234/182680. PMID 31171357. S2CID 174814822.
  3. "Police and drug agency issue strong warning after new drug detected in Dunedin". New Zealand Herald. 8 December 2021.
  4. "Europol 2014 Annual Report on the implementation of Council Decision" (PDF). European Monitoring Centre for Drugs and Drug Addiction (EMCDDA) – Europol. 2005/387/JHA.
  5. "Synthetic Stimulant Market Rapidly Changing as N,N-Dimethylpentylone Replaces Eutylone in Drug Supply Typically Sold as "Ecstasy" or "Molly"". 20 April 2022.
  6. "2020 - Placement of N-Ethylpentylone in Schedule I".
  7. "2007 - Definition of 'Positional Isomer' as It Pertains to the Control of Schedule I Controlled Substances".
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