ARPC2

Actin related protein 2/3 complex subunit 2
المعرفات
الأسماء المستعارة	p34-ARC, ARPC2, arp2/3 complex 34 kDa subunit, testis tissue sperm-binding protein Li 53e, actin related protein 2/3 complex, subunit 2, 34kDa, ARP2/3 protein complex subunit 34, actin-related protein 2/3 complex subunit 2
معرفات خارجية
أورثولوج
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	ويكي بيانات
اعرض/عدّل إنسان

ARPC2‏ (Actin related protein 2/3 complex subunit 2) هوَ بروتين يُشَفر بواسطة جين ARPC2 في الإنسان.[1][2][3]

الوظيفة

المراجع

"Entrez Gene: ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa"، مؤرشف من الأصل في 05 ديسمبر 2010.
Welch MD, DePace AH, Verma S, Iwamatsu A, Mitchison TJ (أغسطس 1997)، "The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly"، J. Cell Biol.، 138 (2): 375–84، doi:10.1083/jcb.138.2.375، PMC 2138188، PMID 9230079.
Machesky LM, Reeves E, Wientjes F, Mattheyse FJ, Grogan A, Totty NF, Burlingame AL, Hsuan JJ, Segal AW (1997)، "Mammalian actin-related protein 2/3 complex localizes to regions of lamellipodial protrusion and is composed of evolutionarily conserved proteins"، Biochem. J.، 328 ( Pt 1) (Pt 1): 105–12، PMC 1218893، PMID 9359840.

قراءة متعمقة

Couch FJ, Rommens JM, Neuhausen SL, Bélanger C, Dumont M, Abel K, Bell R, Berry S, Bogden R, Cannon-Albright L, Farid L, Frye C, Hattier T, Janecki T, Jiang P, Kehrer R, Leblanc JF, McArthur-Morrison J, Meney D, Miki Y, Peng Y, Samson C, Schroeder M, Snyder SC, Simard J (1996)، "Generation of an integrated transcription map of the BRCA2 region on chromosome 13q12-q13"، Genomics، 36 (1): 86–99، doi:10.1006/geno.1996.0428، PMID 8812419.
Welch MD, Iwamatsu A, Mitchison TJ (1997)، "Actin polymerization is induced by Arp2/3 protein complex at the surface of Listeria monocytogenes"، Nature، 385 (6613): 265–9، doi:10.1038/385265a0، PMID 9000076.
Näär AM, Beaurang PA, Zhou S, Abraham S, Solomon W, Tjian R (1999)، "Composite co-activator ARC mediates chromatin-directed transcriptional activation"، Nature، 398 (6730): 828–32، doi:10.1038/19789، PMID 10235267.
Zhao X, Yang Z, Qian M, Zhu X (2001)، "Interactions among subunits of human Arp2/3 complex: p20-Arc as the hub"، Biochem. Biophys. Res. Commun.، 280 (2): 513–7، doi:10.1006/bbrc.2000.4151، PMID 11162547.
Robinson RC, Turbedsky K, Kaiser DA, Marchand JB, Higgs HN, Choe S, Pollard TD (2001)، "Crystal structure of Arp2/3 complex"، Science، 294 (5547): 1679–84، doi:10.1126/science.1066333، PMID 11721045.
Gournier H, Goley ED, Niederstrasser H, Trinh T, Welch MD (2001)، "Reconstitution of human Arp2/3 complex reveals critical roles of individual subunits in complex structure and activity"، Mol. Cell، 8 (5): 1041–52، doi:10.1016/S1097-2765(01)00393-8، PMID 11741539.
Gevaert K, Goethals M, Martens L, Van Damme J, Staes A, Thomas GR, Vandekerckhove J (2003)، "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides"، Nat. Biotechnol.، 21 (5): 566–9، doi:10.1038/nbt810، PMID 12665801.
Kaneda A, Kaminishi M, Sugimura T, Ushijima T (2004)، "Decreased expression of the seven ARP2/3 complex genes in human gastric cancers"، Cancer Lett.، 212 (2): 203–10، doi:10.1016/j.canlet.2004.03.020، PMID 15279900.
Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M (2005)، "Nucleolar proteome dynamics"، Nature، 433 (7021): 77–83، doi:10.1038/nature03207، PMID 15635413.
Dubois T, Paléotti O, Mironov AA, Fraisier V, Stradal TE, De Matteis MA, Franco M, Chavrier P (2005)، "Golgi-localized GAP for Cdc42 functions downstream of ARF1 to control Arp2/3 complex and F-actin dynamics"، Nat. Cell Biol.، 7 (4): 353–64، doi:10.1038/ncb1244، PMID 15793564.
Cai L, Holoweckyj N, Schaller MD, Bear JE (2005)، "Phosphorylation of coronin 1B by protein kinase C regulates interaction with Arp2/3 and cell motility"، J. Biol. Chem.، 280 (36): 31913–23، doi:10.1074/jbc.M504146200، PMID 16027158.
Cai L, Marshall TW, Uetrecht AC, Schafer DA, Bear JE (2007)، "Coronin 1B coordinates Arp2/3 complex and cofilin activities at the leading edge"، Cell، 128 (5): 915–29، doi:10.1016/j.cell.2007.01.031، PMC 2630706، PMID 17350576.
Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007)، "Large-scale mapping of human protein-protein interactions by mass spectrometry"، Mol. Syst. Biol.، 3 (1): 89، doi:10.1038/msb4100134، PMC 1847948، PMID 17353931.

بوابة الكيمياء الحيوية
بوابة علم الأحياء الخلوي والجزيئي
بوابة طب

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[entrez-1] "Entrez Gene: ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa"، مؤرشف من الأصل في 05 ديسمبر 2010.

[pmid9230079-2] Welch MD, DePace AH, Verma S, Iwamatsu A, Mitchison TJ (أغسطس 1997)، "The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly"، J. Cell Biol.، 138 (2): 375–84، doi:10.1083/jcb.138.2.375، PMC 2138188، PMID 9230079.

[pmid9359840-3] Machesky LM, Reeves E, Wientjes F, Mattheyse FJ, Grogan A, Totty NF, Burlingame AL, Hsuan JJ, Segal AW (1997)، "Mammalian actin-related protein 2/3 complex localizes to regions of lamellipodial protrusion and is composed of evolutionarily conserved proteins"، Biochem. J.، 328 ( Pt 1) (Pt 1): 105–12، PMC 1218893، PMID 9359840.