REG3A
REG3A (Regenerating family member 3 alpha) هوَ بروتين يُشَفر بواسطة جين REG3A في الإنسان.[1][2][3][3][4][5]
الوظيفة
المراجع
- Vaishnava, Shipra؛ Yamamoto, Miwako؛ Severson, Kari M.؛ Ruhn, Kelly A.؛ Yu, Xiaofei؛ Koren, Omry؛ Ley, Ruth؛ Wakeland, Edward K.؛ Hooper, Lora V. (14 أكتوبر 2011)، "The antibacterial lectin RegIIIγ promotes the spatial segregation of microbiota and host in the intestine"، Science، 334 (6053): 255–258، doi:10.1126/science.1209791، ISSN 0036-8075، PMC 3321924، PMID 21998396.
- Cash, Heather L.؛ Whitham, Cecilia V.؛ Behrendt, Cassie L.؛ Hooper, Lora V. (25 أغسطس 2006)، "Symbiotic bacteria direct expression of an intestinal bactericidal lectin"، Science، 313 (5790): 1126–1130، doi:10.1126/science.1127119، ISSN 1095-9203، PMC 2716667، PMID 16931762.
- "Entrez Gene: REG3A regenerating islet-derived 3 alpha"، مؤرشف من الأصل في 05 ديسمبر 2010.
- "Molecular cloning, genomic organization, and chromosomal localization of the human pancreatitis-associated protein (PAP) gene"، Genomics، 19 (1): 108–14، يونيو 1994، doi:10.1006/geno.1994.1019، PMID 8188210.
- "Plasma clearance, tissue uptake and expression of pituitary peptide 23/pancreatitis-associated protein in the rat."، Journal of Endocrinology، يونيو 1995، PMID 7636430.
قراءة متعمقة
- "A novel gene (HIP) activated in human primary liver cancer"، Cancer Res.، 52 (18): 5089–95، 1992، PMID 1325291.
- "Human pancreatitis-associated protein. Messenger RNA cloning and expression in pancreatic diseases"، J. Clin. Invest.، 90 (6): 2284–91، 1993، doi:10.1172/JCI116115، PMC 443380، PMID 1469087.
- "Cloning and tissue-specific expression of cDNAs for the human and mouse homologues of rat pancreatitis-associated protein (PAP)"، Biochim. Biophys. Acta، 1172 (1–2): 184–6، 1993، doi:10.1016/0167-4781(93)90290-t، PMID 7679928.
- "The human pancreatitis-associated protein (PAP)-encoding gene generates multiple transcripts through alternative use of 5' exons"، Gene، 155 (2): 283–7، 1995، doi:10.1016/0378-1119(94)00799-X، PMID 7721106.
- "Structural organization and chromosomal localization of a human gene (HIP/PAP) encoding a C-type lectin overexpressed in primary liver cancer"، Eur. J. Biochem.، 224 (1): 29–38، 1994، doi:10.1111/j.1432-1033.1994.tb19991.x، PMID 8076648.
- "HIP/PAP is an adhesive protein expressed in hepatocarcinoma, normal Paneth, and pancreatic cells"، Am. J. Physiol.، 271 (6 Pt 1): G993–1002، 1997، PMID 8997243.
- "Cloning and sequencing of the pancreatic islet neogenesis associated protein (INGAP) gene and its expression in islet neogenesis in hamsters"، J. Clin. Invest.، 99 (9): 2100–9، 1997، doi:10.1172/JCI119383، PMC 508040، PMID 9151782.
- "PAP I interacts with itself, PAP II, PAP III, and lithostathine/regIalpha"، Mol. Cell Biol. Res. Commun.، 2 (3): 150–4، 2000، doi:10.1006/mcbr.1999.0166، PMID 10662590.
- "A family of 16-kDa pancreatic secretory stress proteins form highly organized fibrillar structures upon tryptic activation"، J. Biol. Chem.، 276 (24): 21028–38، 2001، doi:10.1074/jbc.M010717200، PMID 11278730.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences"، Proc. Natl. Acad. Sci. U.S.A.، 99 (26): 16899–903، 2003، doi:10.1073/pnas.242603899، PMC 139241، PMID 12477932.
- "HIP/PAP stimulates liver regeneration after partial hepatectomy and combines mitogenic and anti-apoptotic functions through the PKA signaling pathway"، FASEB J.، 17 (11): 1441–50، 2003، doi:10.1096/fj.02-1013com، PMID 12890698.
- "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)"، Genome Res.، 14 (10B): 2121–7، 2004، doi:10.1101/gr.2596504، PMC 528928، PMID 15489334.
- "HIP/PAP accelerates liver regeneration and protects against acetaminophen injury in mice"، Hepatology، 42 (3): 618–26، 2005، doi:10.1002/hep.20845، PMID 16116631.
- "Towards a proteome-scale map of the human protein-protein interaction network"، Nature، 437 (7062): 1173–8، 2005، doi:10.1038/nature04209، PMID 16189514.
- "Symbiotic Bacteria Direct Expression of an Intestinal Bactericidal Lectin"، Science، 313 (5790): 1126–30، 2006، doi:10.1126/science.1127119، PMC 2716667، PMID 16931762.
- "Human pancreatitis-associated protein forms fibrillar aggregates with a native-like conformation"، J. Biol. Chem.، 281 (44): 33566–76، 2006، doi:10.1074/jbc.M604513200، PMID 16963458.
بوابة علم الأحياء الخلوي والجزيئي
بوابة الكيمياء الحيوية
بوابة طب
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