SLC5A6

Solute carrier family 5 member 6
المعرفات
الأسماء المستعارة	Na+-dependent multivitamin transporter, sodium-dependent multivitamin transporter, solute carrier family 5 (sodium-dependent vitamin transporter), member 6, Na(+)-dependent multivitamin transporter, SLC5A6, solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
معرفات خارجية
أورثولوج
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	ويكي بيانات
اعرض/عدّل إنسان

SLC5A6‏ (Solute carrier family 5 member 6) هوَ بروتين يُشَفر بواسطة جين SLC5A6 في الإنسان.[1][2][3][4]

الوظيفة

المراجع

Uchida Y, Ito K, Ohtsuki S, Kubo Y, Suzuki T, Terasaki T (2015)، "Major involvement of Na(+) -dependent multivitamin transporter (SLC5A6/SMVT) in uptake of biotin and pantothenic acid by human brain capillary endothelial cells"، Journal of Neurochemistry، 134 (1): 97–112، doi:10.1111/jnc.13092، PMID 25809983.
"Entrez Gene: SLC5A6 solute carrier family 5 (sodium-dependent vitamin transporter), member 6"، مؤرشف من الأصل في 05 ديسمبر 2010.
Wang H, Huang W, Fei YJ, Xia H, Yang-Feng TL, Leibach FH, Devoe LD, Ganapathy V, Prasad PD (يوليو 1999)، "Human placental Na+-dependent multivitamin transporter. Cloning, functional expression, gene structure, and chromosomal localization"، J Biol Chem، 274 (21): 14875–83، doi:10.1074/jbc.274.21.14875، PMID 10329687.
Prasad PD, Wang H, Kekuda R, Fujita T, Fei YJ, Devoe LD, Leibach FH, Ganapathy V (أبريل 1998)، "Cloning and functional expression of a cDNA encoding a mammalian sodium-dependent vitamin transporter mediating the uptake of pantothenate, biotin, and lipoate"، J Biol Chem، 273 (13): 7501–6، doi:10.1074/jbc.273.13.7501، PMID 9516450.

قراءة متعمقة

Prasad PD, Wang H, Huang W, وآخرون (1999)، "Molecular and functional characterization of the intestinal Na+-dependent multivitamin transporter."، Arch. Biochem. Biophys.، 366 (1): 95–106، doi:10.1006/abbi.1999.1213، PMID 10334869.
Zempleni J, Steven Stanley J, Mock DM (2001)، "Proliferation of peripheral blood mononuclear cells causes increased expression of the sodium-dependent multivitamin transporter gene and increased uptake of pantothenic acidopen star"، The Journal of Nutritional Biochemistry، 12 (8): 465–473، doi:10.1016/S0955-2863(01)00162-0، PMID 11834205.
Dey S, Subramanian VS, Chatterjee NS, وآخرون (2002)، "Characterization of the 5' regulatory region of the human sodium-dependent multivitamin transporter, hSMVT."، Biochim. Biophys. Acta، 1574 (2): 187–92، doi:10.1016/s0167-4781(02)00226-9، PMID 11955628.
Strausberg RL, Feingold EA, Grouse LH, وآخرون (2003)، "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences"، Proc. Natl. Acad. Sci. U.S.A.، 99 (26): 16899–903، doi:10.1073/pnas.242603899، PMC 139241، PMID 12477932.
Balamurugan K, Ortiz A, Said HM (2003)، "Biotin uptake by human intestinal and liver epithelial cells: role of the SMVT system"، Am. J. Physiol. Gastrointest. Liver Physiol.، 285 (1): G73–7، doi:10.1152/ajpgi.00059.2003، PMID 12646417.
Ota T, Suzuki Y, Nishikawa T, وآخرون (2004)، "Complete sequencing and characterization of 21,243 full-length human cDNAs"، Nat. Genet.، 36 (1): 40–5، doi:10.1038/ng1285، PMID 14702039.
Balamurugan K, Vaziri ND, Said HM (2005)، "Biotin uptake by human proximal tubular epithelial cells: cellular and molecular aspects"، Am. J. Physiol. Renal Physiol.، 288 (4): F823–31، doi:10.1152/ajprenal.00375.2004، PMID 15561972.
Otsuki T, Ota T, Nishikawa T, وآخرون (2007)، "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries"، DNA Res.، 12 (2): 117–26، doi:10.1093/dnares/12.2.117، PMID 16303743.
Luo S, Kansara VS, Zhu X, وآخرون (2006)، "Functional Characterization of Sodium-dependent Multivitamin Transporter (SMVT) in MDCK-MDR1 cells and its Utilization as a Target for Drug Delivery"، Mol. Pharm.، 3 (3): 329–39، doi:10.1021/mp0500768، PMC 2553563، PMID 16749865.
Reidling JC, Nabokina SM, Said HM (2007)، "Molecular mechanisms involved in the adaptive regulation of human intestinal biotin uptake: A study of the hSMVT system"، Am. J. Physiol. Gastrointest. Liver Physiol.، 292 (1): G275–81، doi:10.1152/ajpgi.00327.2006، PMID 16959947.
Reidling JC, Said HM (2007)، "Regulation of the human biotin transporter hSMVT promoter by KLF-4 and AP-2: confirmation of promoter activity in vivo"، Am. J. Physiol., Cell Physiol.، 292 (4): C1305–12، doi:10.1152/ajpcell.00360.2006، PMID 17135299.

بوابة الكيمياء الحيوية
بوابة علم الأحياء الخلوي والجزيئي
بوابة طب

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[Uchida_2015-1] Uchida Y, Ito K, Ohtsuki S, Kubo Y, Suzuki T, Terasaki T (2015)، "Major involvement of Na(+) -dependent multivitamin transporter (SLC5A6/SMVT) in uptake of biotin and pantothenic acid by human brain capillary endothelial cells"، Journal of Neurochemistry، 134 (1): 97–112، doi:10.1111/jnc.13092، PMID 25809983.

[entrez-2] "Entrez Gene: SLC5A6 solute carrier family 5 (sodium-dependent vitamin transporter), member 6"، مؤرشف من الأصل في 05 ديسمبر 2010.

[pmid10329687-3] Wang H, Huang W, Fei YJ, Xia H, Yang-Feng TL, Leibach FH, Devoe LD, Ganapathy V, Prasad PD (يوليو 1999)، "Human placental Na+-dependent multivitamin transporter. Cloning, functional expression, gene structure, and chromosomal localization"، J Biol Chem، 274 (21): 14875–83، doi:10.1074/jbc.274.21.14875، PMID 10329687.

[pmid9516450-4] Prasad PD, Wang H, Kekuda R, Fujita T, Fei YJ, Devoe LD, Leibach FH, Ganapathy V (أبريل 1998)، "Cloning and functional expression of a cDNA encoding a mammalian sodium-dependent vitamin transporter mediating the uptake of pantothenate, biotin, and lipoate"، J Biol Chem، 273 (13): 7501–6، doi:10.1074/jbc.273.13.7501، PMID 9516450.