Fenoxazoline

Fenoxazoline
Clinical data
Trade namesAturgyl, Nasofelin, Nebulicina
AHFS/Drugs.comInternational Drug Names
Routes of
administration
Topical (nasal solution)
ATC code
Legal status
Legal status
  • ℞-only (BR)
Identifiers
IUPAC name
  • 2-[(2-propan-2-ylphenoxy)methyl]-4,5-dihydro-1H-imidazole
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.023.124
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Chemical and physical data
FormulaC13H18N2O
Molar mass218.300 g·mol−1
3D model (JSmol)
SMILES
  • CC(C)C1=CC=CC=C1OCC2=NCCN2
InChI
  • InChI=1S/C13H18N2O/c1-10(2)11-5-3-4-6-12(11)16-9-13-14-7-8-15-13/h3-6,10H,7-9H2,1-2H3,(H,14,15) ☒N
  • Key:GFYSWQDCHLWRMQ-UHFFFAOYSA-N ☒N
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Fenoxazoline (trade name Aturgyl in Brazil) is a nasal decongestant.[1]

Fenmetozole has the precise same formula, albeit instead of an ortho-isopropyl group, 3',4'-dich was chosen instead.


References

  1. Lorino AM, Lofaso F, Dahan E, Coste A, Harf A, Lorino H (June 1999). "Combined effects of a mechanical nasal dilator and a topical decongestant on nasal airflow resistance". Chest. 115 (6): 1514–8. doi:10.1378/chest.115.6.1514. PMID 10378542.
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