Fenoxazoline

Fenoxazoline
Clinical data
Trade names	Aturgyl, Nasofelin, Nebulicina
AHFS/Drugs.com	International Drug Names
Routes of; administration	Topical (nasal solution)
ATC code	R01AA12 (WHO) ;
Legal status
Legal status	℞-only (BR);
Identifiers
	IUPAC name 2-[(2-propan-2-ylphenoxy)methyl]-4,5-dihydro-1H-imidazole;
CAS Number	4846-91-7 ;
PubChem CID	71899;
ChemSpider	64911 ;
UNII	97JJW1W1R3;
KEGG	D07372 ;
ChEMBL	ChEMBL14012 ;
CompTox Dashboard (EPA)	DTXSID30197533 ;
ECHA InfoCard	100.023.124
Chemical and physical data
Formula	C13H18N2O
Molar mass	218.300 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(C)C1=CC=CC=C1OCC2=NCCN2;
	InChI InChI=1S/C13H18N2O/c1-10(2)11-5-3-4-6-12(11)16-9-13-14-7-8-15-13/h3-6,10H,7-9H2,1-2H3,(H,14,15) ; Key:GFYSWQDCHLWRMQ-UHFFFAOYSA-N ;
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Fenoxazoline (trade name Aturgyl in Brazil) is a nasal decongestant.^[1]

Fenmetozole has the precise same formula, albeit instead of an ortho-isopropyl group, 3',4'-dich was chosen instead.

References

↑ Lorino AM, Lofaso F, Dahan E, Coste A, Harf A, Lorino H (June 1999). "Combined effects of a mechanical nasal dilator and a topical decongestant on nasal airflow resistance". Chest. 115 (6): 1514–8. doi:10.1378/chest.115.6.1514. PMID 10378542.

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