Thonzylamine

Thonzylamine
Clinical data
Other namesNeohetramine
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
IUPAC name
  • N-(4-methoxybenzyl)-N',N'-dimethyl-N-pyrimidin-2-ylethane-1,2-diamine
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.001.913
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Chemical and physical data
FormulaC16H22N4O
Molar mass286.379 g·mol−1
3D model (JSmol)
SMILES
  • n1cccnc1N(CCN(C)C)Cc2ccc(OC)cc2
InChI
  • InChI=1S/C16H22N4O/c1-19(2)11-12-20(16-17-9-4-10-18-16)13-14-5-7-15(21-3)8-6-14/h4-10H,11-13H2,1-3H3 checkY
  • Key:GULNIHOSWFYMRN-UHFFFAOYSA-N checkY
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Thonzylamine (or neohetramine)[1] is an antihistamine and anticholinergic used as an antipruritic.

Synthesis

Thonzylamine synthesis: H. L. Friedman and A, V. Tolstouhov, U.S. Patent 2,465,865 (1949).

See also

References

  1. ↑ Arminio JJ, Sweet CC (December 1949). "The prophylaxis and treatment of the common cold with neohetramine (thonzylamine hydrochloride)". Industrial Medicine & Surgery. 18 (12): 509–11. PMID 15393969.
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