Deptropine

Deptropine
Clinical data
ATC code
Identifiers
IUPAC name
  • 3a-[(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)
    oxy]1aH,5aH-tropane
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.009.154
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Chemical and physical data
FormulaC23H27NO
Molar mass333.475 g·mol−1
3D model (JSmol)
SMILES
  • CN5[C@@H]1CC[C@H]5C[C@H](C1)OC3c4ccccc4CCc2ccccc23
InChI
  • InChI=1S/C23H27NO/c1-24-18-12-13-19(24)15-20(14-18)25-23-21-8-4-2-6-16(21)10-11-17-7-3-5-9-22(17)23/h2-9,18-20,23H,10-15H2,1H3/t18-,19+,20+ checkY
  • Key:ZWPODSUQWXAZNC-PMOLBWCYSA-N checkY
  (verify)

Deptropine (Brontina) also known as dibenzheptropine, is an antihistamine with anticholinergic properties acting at the H1 receptor.[1] It is usually marketed as the citrate salt.[2]

References

  1. ↑ PubChem. "Deptropine". pubchem.ncbi.nlm.nih.gov. Retrieved 2020-11-16.
  2. ↑ Leckie WJ, Horne NW (July 1965). "Preliminary Assessment of Deptropine Dihydrogen Citrate in Chronic Airways Obstruction". Thorax. 20 (4): 317–23. doi:10.1136/thx.20.4.317. PMC 1018942. PMID 14321719.
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