Ethinylestradiol/norethisterone

Not to be confused with Ethinylestradiol/norethisterone acetate.
Ethinylestradiol/norethisterone
Combination of
EthinylestradiolEstrogen
NorethisteroneProgestogen
Names
Trade namesAlyacen, Aranelle, Balziva, others
Other namesEE/NET
Clinical data
WHO AWaReUnlinkedWikibase error: ⧼unlinkedwikibase-error-statements-entity-not-set⧽
Pregnancy
category
  • US: X (Contraindicated)
    Routes of
    use    		By mouth
    Defined daily dosenot established[1]
    External links
    AHFS/Drugs.comMonograph
    MedlinePlusa601050
    Legal
    Legal status

    Ethinylestradiol/norethisterone (EE/NET), or ethinylestradiol/norethindrone, is a combination birth control pill which contains ethinylestradiol (EE), an estrogen and norethisterone (NET), a progestin.[2] It is used for birth control, symptoms of menstruation, endometriosis, and menopausal symptoms.[2][3] Other uses include acne.[2] It is taken by mouth.[2]

    Side effects can include nausea, headache, blood clots, breast pain, depression, and liver problems.[3] Use is not recommended during pregnancy, the initial three weeks after childbirth, and in those at high risk of blood clots.[3][4] It; however, may be started immediately after a miscarriage or abortion.[4] Smoking while using combined birth control pills is not recommended.[5] It works by stopping ovulation, making the uterus not suitable for implantation, and making the mucus at the opening to the cervix thick.[4]

    This combination pill was approved for medical use in the United States in 1964.[6] It is on the World Health Organization's List of Essential Medicines.[7] It is available as a generic medication.[8] In the United Kingdom three months of medication costs the NHS about £2.70.[9] In the United States it costs about $25–50 per month.[8] It is marketed under a large number of brand names.[10] In 2017, it was the 53rd most commonly prescribed medication in the United States, with more than fourteen million prescriptions.[11][12]

    Dosage

    The defined daily dose is not established.[1]

    Society and culture

    Cost

    In the United Kingdom three months of medication costs the NHS about £2.70.[9] In the United States it costs about $25–50 per month.[8] In 2017, it was the 53rd most commonly prescribed medication in the United States, with more than fourteen million prescriptions.[11][12]

    • EthinylEstradiolNorethindrone costs (US)
      EthinylEstradiolNorethindrone costs (US)
    • EthinylEstradiolNorethindrone prescriptions (US)
      EthinylEstradiolNorethindrone prescriptions (US)

    See also

    References

    1. 1 2 "WHOCC - ATC/DDD Index". www.whocc.no. Archived from the original on 28 August 2021. Retrieved 17 September 2020.
    2. 1 2 3 4 "Ethinyl estradiol and norethindrone (HRT) medical facts from Drugs.com". www.drugs.com. Archived from the original on 24 December 2016. Retrieved 23 December 2016.
    3. 1 2 3 World Health Organization (2009). Stuart MC, Kouimtzi M, Hill SR (eds.). WHO Model Formulary 2008. World Health Organization. p. 365. hdl:10665/44053. ISBN 9789241547659.
    4. 1 2 3 "Brevinor Tablets - Summary of Product Characteristics (SPC) - (eMC)". www.medicines.org.uk. Archived from the original on 24 December 2016. Retrieved 23 December 2016.
    5. ↑ "Estrogen-Progestin Combinations". The American Society of Health-System Pharmacists. Archived from the original on 23 December 2016. Retrieved 8 December 2016.
    6. ↑ Haussman, Melissa (2013). Reproductive Rights and the State: Getting the Birth Control, RU-486, Morning-after Pills and the Gardasil Vaccine to the U.S. Market. ABC-CLIO. p. 72. ISBN 9780313398223. Archived from the original on 2016-12-24.
    7. ↑ World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
    8. 1 2 3 Hamilton, Richart (2015). Tarascon Pocket Pharmacopoeia 2015 Deluxe Lab-Coat Edition. Jones & Bartlett Learning. p. 353. ISBN 9781284057560.
    9. 1 2 British national formulary : BNF 69 (69 ed.). British Medical Association. 2015. p. 552. ISBN 9780857111562.
    10. ↑ "Alyacen 1/35 (birth control) medical facts from Drugs.com". www.drugs.com. Archived from the original on 2016-12-24.
    11. 1 2 "The Top 300 of 2020". ClinCalc. Archived from the original on 12 February 2021. Retrieved 11 April 2020.
    12. 1 2 "Ethinyl Estradiol; Norethindrone - Drug Usage Statistics". ClinCalc. Archived from the original on 27 January 2021. Retrieved 11 April 2020.
    Identifiers:
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