CAPN2
CAPN2 (Calpain 2) هوَ بروتين يُشَفر بواسطة جين CAPN2 في الإنسان.[1][2]
المراجع
- "Tandemly reiterated negative enhancer-like elements regulate transcription of a human gene for the large subunit of calcium-dependent protease"، J. Biol. Chem.، 264 (11): 6404–11، مايو 1989، PMID 2539381.
- "Molecular cloning of the cDNA for the large subunit of the high-Ca2+-requiring form of human Ca2+-activated neutral protease"، Biochemistry، 27 (21): 8122–8، 1988، doi:10.1021/bi00421a022، PMID 2852952.
قراءة متعمقة
- "Calpain: novel family members, activation, and physiologic function"، Biol. Chem. Hoppe-Seyler، 376 (9): 523–9، 1995، PMID 8561910.
- "Caspases: the executioners of apoptosis"، Biochem. J.، 326 (Pt 1): 1–16، 1997، doi:10.1042/bj3260001، PMC 1218630، PMID 9337844.
- "The structure of calcium-free human m-calpain: implications for calcium activation and function"، Trends Cardiovasc. Med.، 11 (6): 222–9، 2001، doi:10.1016/S1050-1738(01)00112-8، PMID 11673052.
- "Reproducibility of response to a questionnaire on symptoms of masticatory dysfunction"، Community Dent Oral Epidemiol، 4 (5): 205–9، 1976، doi:10.1111/j.1600-0528.1976.tb00985.x، PMID 1067155.
- "Expression of calpain II gene in human hematopoietic system cells infected with human T-cell leukemia virus type I"، J. Biol. Chem.، 267 (27): 19373–8، 1992، PMID 1527057.
- "Four genes for the calpain family locate on four distinct human chromosomes"، Cytogenet. Cell Genet.، 53 (4): 225–9، 1990، doi:10.1159/000132937، PMID 2209092.
- "Interaction of human calpains I and II with high molecular weight and low molecular weight kininogens and their heavy chain: mechanism of interaction and the role of divalent cations"، Biochemistry، 26 (10): 2863–70، 1987، doi:10.1021/bi00384a030، PMID 3038169.
- "The Ced-3/interleukin 1beta converting enzyme-like homolog Mch6 and the lamin-cleaving enzyme Mch2alpha are substrates for the apoptotic mediator CPP32"، J. Biol. Chem.، 271 (43): 27099–106، 1996، doi:10.1074/jbc.271.43.27099، PMID 8900201.
- "NMDA and HIV-1 coat protein, GP120, produce necrotic but not apoptotic cell death in human CHP100 neuroblastoma cultures via a mechanism involving calpain"، Biochem. Biophys. Res. Commun.، 229 (1): 299–304، 1996، doi:10.1006/bbrc.1996.1796، PMID 8954122.
- "Identification of mu-, m-calpains and calpastatin and capture of mu-calpain activation in endothelial cells"، J. Cell. Biochem.، 66 (2): 197–209، 1997، doi:10.1002/(SICI)1097-4644(19970801)66:2<197::AID-JCB7>3.0.CO;2-L، PMID 9213221.
- "Calcium-dependent signaling pathways in T cells. Potential role of calpain, protein tyrosine phosphatase 1b, and p130Cas in integrin-mediated signaling events"، J. Biol. Chem.، 272 (52): 33377–83، 1997، doi:10.1074/jbc.272.52.33377، PMID 9407132.
- "Expression of three calpain isoform genes in human skeletal muscles"، J. Neurol. Sci.، 155 (2): 163–9، 1998، doi:10.1016/S0022-510X(97)00309-2، PMID 9562261.
- "The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium"، Proc. Natl. Acad. Sci. U.S.A.، 97 (2): 588–92، 2000، doi:10.1073/pnas.97.2.588، PMC 15374، PMID 10639123.
- "Crystallization and preliminary X-ray analysis of recombinant full-length human m-calpain"، Acta Crystallogr. D، 56 (Pt 1): 73–5، 2000، doi:10.1107/S0907444999013748، PMID 10666632.
- "Direct cleavage by the calcium-activated protease calpain can lead to inactivation of caspases"، J. Biol. Chem.، 275 (7): 5131–5، 2000، doi:10.1074/jbc.275.7.5131، PMID 10671558.
- "Neurotoxicity induces cleavage of p35 to p25 by calpain"، Nature، 405 (6784): 360–4، 2000، doi:10.1038/35012636، PMID 10830966.
بوابة طب
بوابة علم الأحياء الخلوي والجزيئي
بوابة الكيمياء الحيوية
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