TXNIP

thioredoxin interacting protein
المعرفات
الأسماء المستعارة	thioredoxin binding protein 2, TXNIP, upregulated by 1,25-dihydroxyvitamin D-3, thioredoxin-interacting protein, Thioredoxin-binding protein 2, vitamin D3 up-regulated protein 1
معرفات خارجية
أورثولوج
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	ويكي بيانات
اعرض/عدّل إنسان

TXNIP‏ (Thioredoxin interacting protein) هوَ بروتين يُشَفر بواسطة جين TXNIP في الإنسان.[1][2]

المراجع

Chen KS, DeLuca HF (سبتمبر 1994)، "Isolation and characterization of a novel cDNA from HL-60 cells treated with 1,25-dihydroxyvitamin D-3"، Biochimica et Biophysica Acta، 1219 (1): 26–32، doi:10.1016/0167-4781(94)90242-9، PMID 8086474.
"Entrez Gene: TXNIP thioredoxin interacting protein"، مؤرشف من الأصل في 05 ديسمبر 2010.

قراءة متعمقة

Nishiyama A, Matsui M, Iwata S, Hirota K, Masutani H, Nakamura H, Takagi Y, Sono H, Gon Y, Yodoi J (يوليو 1999)، "Identification of thioredoxin-binding protein-2/vitamin D(3) up-regulated protein 1 as a negative regulator of thioredoxin function and expression"، The Journal of Biological Chemistry، 274 (31): 21645–50، doi:10.1074/jbc.274.31.21645، PMID 10419473.
Ludwig DL, Kotanides H, Le T, Chavkin D, Bohlen P, Witte L (مايو 2001)، "Cloning, genetic characterization, and chromosomal mapping of the mouse VDUP1 gene"، Gene، 269 (1–2): 103–12، doi:10.1016/S0378-1119(01)00455-3، PMID 11376942.
Bodnar JS, Chatterjee A, Castellani LW, Ross DA, Ohmen J, Cavalcoli J, Wu C, Dains KM, Catanese J, Chu M, Sheth SS, Charugundla K, Demant P, West DB, de Jong P, Lusis AJ (يناير 2002)، "Positional cloning of the combined hyperlipidemia gene Hyplip1"، Nature Genetics، 30 (1): 110–6، doi:10.1038/ng811، PMC 2846781، PMID 11753387.
Joguchi A, Otsuka I, Minagawa S, Suzuki T, Fujii M, Ayusawa D (أبريل 2002)، "Overexpression of VDUP1 mRNA sensitizes HeLa cells to paraquat"، Biochemical and Biophysical Research Communications، 293 (1): 293–7، doi:10.1016/S0006-291X(02)00208-5، PMID 12054598.
Butler LM, Zhou X, Xu WS, Scher HI, Rifkind RA, Marks PA, Richon VM (سبتمبر 2002)، "The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin"، Proceedings of the National Academy of Sciences of the United States of America، 99 (18): 11700–5، doi:10.1073/pnas.182372299، PMC 129332، PMID 12189205.
Schulze PC, De Keulenaer GW, Yoshioka J, Kassik KA, Lee RT (أكتوبر 2002)، "Vitamin D3-upregulated protein-1 (VDUP-1) regulates redox-dependent vascular smooth muscle cell proliferation through interaction with thioredoxin"، Circulation Research، 91 (8): 689–95، doi:10.1161/01.RES.0000037982.55074.F6، PMID 12386145.
Han SH, Jeon JH, Ju HR, Jung U, Kim KY, Yoo HS, Lee YH, Song KS, Hwang HM, Na YS, Yang Y, Lee KN, Choi I (يونيو 2003)، "VDUP1 upregulated by TGF-beta1 and 1,25-dihydorxyvitamin D3 inhibits tumor cell growth by blocking cell-cycle progression"، Oncogene، 22 (26): 4035–46، doi:10.1038/sj.onc.1206610، PMID 12821938.
Champliaud MF, Viel A, Baden HP (أكتوبر 2003)، "The expression of vitamin D-upregulated protein 1 in skin and its interaction with sciellin in cultured keratinocytes"، The Journal of Investigative Dermatology، 121 (4): 781–5، doi:10.1046/j.1523-1747.2003.12539.x، PMID 14632196.
Kim KY, Shin SM, Kim JK, Paik SG, Yang Y, Choi I (مارس 2004)، "Heat shock factor regulates VDUP1 gene expression"، Biochemical and Biophysical Research Communications، 315 (2): 369–75، doi:10.1016/j.bbrc.2004.01.047، PMID 14766217.
Schulze PC, Yoshioka J, Takahashi T, He Z, King GL, Lee RT (يوليو 2004)، "Hyperglycemia promotes oxidative stress through inhibition of thioredoxin function by thioredoxin-interacting protein"، The Journal of Biological Chemistry، 279 (29): 30369–74، doi:10.1074/jbc.M400549200، PMID 15128745.
Coon H, Singh N, Dunn D, Eckfeldt JH, Province MA, Hopkins PN, Weiss R, Hunt SC, Leppert MF (يونيو 2004)، "TXNIP gene not associated with familial combined hyperlipidemia in the NHLBI Family Heart Study"، Atherosclerosis، 174 (2): 357–62، doi:10.1016/j.atherosclerosis.2004.02.004، PMID 15136067.
Nishinaka Y, Masutani H, Oka S, Matsuo Y, Yamaguchi Y, Nishio K, Ishii Y, Yodoi J (سبتمبر 2004)، "Importin alpha1 (Rch1) mediates nuclear translocation of thioredoxin-binding protein-2/vitamin D(3)-up-regulated protein 1"، The Journal of Biological Chemistry، 279 (36): 37559–65، doi:10.1074/jbc.M405473200، PMID 15234975.
Aitken CJ, Hodge JM, Nishinaka Y, Vaughan T, Yodoi J, Day CJ, Morrison NA, Nicholson GC (ديسمبر 2004)، "Regulation of human osteoclast differentiation by thioredoxin binding protein-2 and redox-sensitive signaling"، Journal of Bone and Mineral Research، 19 (12): 2057–64، doi:10.1359/JBMR.040913، PMID 15537450.
Yamawaki H, Pan S, Lee RT, Berk BC (مارس 2005)، "Fluid shear stress inhibits vascular inflammation by decreasing thioredoxin-interacting protein in endothelial cells"، The Journal of Clinical Investigation، 115 (3): 733–8، doi:10.1172/JCI23001، PMC 546457، PMID 15696199.
Minn AH, Hafele C, Shalev A (مايو 2005)، "Thioredoxin-interacting protein is stimulated by glucose through a carbohydrate response element and induces beta-cell apoptosis"، Endocrinology، 146 (5): 2397–405، doi:10.1210/en.2004-1378، PMID 15705778.

بوابة طب
بوابة الكيمياء الحيوية
بوابة علم الأحياء الخلوي والجزيئي

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[pmid8086474-1] Chen KS, DeLuca HF (سبتمبر 1994)، "Isolation and characterization of a novel cDNA from HL-60 cells treated with 1,25-dihydroxyvitamin D-3"، Biochimica et Biophysica Acta، 1219 (1): 26–32، doi:10.1016/0167-4781(94)90242-9، PMID 8086474.

[entrez-2] "Entrez Gene: TXNIP thioredoxin interacting protein"، مؤرشف من الأصل في 05 ديسمبر 2010.