ERRFI1
ERRFI1 (ERBB receptor feedback inhibitor 1) هوَ بروتين يُشَفر بواسطة جين ERRFI1 في الإنسان.[1][2][2][3][4][5]
الوظيفة
المراجع
- "Expression of RALT, a feedback inhibitor of ErbB receptors, is subjected to an integrated transcriptional and post-translational control"، Oncogene، 21 (42): 6530–6539، سبتمبر 2002، doi:10.1038/sj.onc.1205823، PMID 12226756.
- "Entrez Gene: ERRFI1 ERBB receptor feedback inhibitor 1"، مؤرشف من الأصل في 05 ديسمبر 2010.
- "Gene 33/Mig-6, a transcriptionally inducible adapter protein that binds GTP-Cdc42 and activates SAPK/JNK. A potential marker transcript for chronic pathologic conditions, such as diabetic nephropathy. Possible role in the response to persistent stress"، J Biol Chem، 275 (23): 17838–17847، يوليو 2000، doi:10.1074/jbc.M909735199، PMC 3668664، PMID 10749885.
- "Rat gene 33: analysis of its structure, messenger RNA and basal promoter activity"، Nucleic Acids Res، 17 (16): 6651–6667، أكتوبر 1989، doi:10.1093/nar/17.16.6651، PMC 318357، PMID 2780291.
- "Inhibition of ErbB-2 mitogenic and transforming activity by RALT, a mitogen-induced signal transducer which binds to the ErbB-2 kinase domain"، Mol Cell Biol، 20 (20): 7735–7750، أكتوبر 2000، doi:10.1128/MCB.20.20.7735-7750.2000، PMC 86354، PMID 11003669.
قراءة متعمقة
- "Mig-6, signal transduction, stress response and cancer"، Cell Cycle، 6 (5): 507–13، 2007، doi:10.4161/cc.6.5.3928، PMID 17351343.
- "Identification of a novel mitogen-inducible gene (mig-6): regulation during G1 progression and differentiation"، Exp. Cell Res.، 219 (2): 527–535، 1995، doi:10.1006/excr.1995.1261، PMID 7641805.
- "Mig-6 is a negative regulator of the epidermal growth factor receptor signal"، Biol. Chem.، 382 (12): 1649–1662، 2002، doi:10.1515/BC.2001.200، PMID 11843178.
- Tsunoda T؛ Inokuchi J؛ Baba I؛ وآخرون (2002)، "A novel mechanism of nuclear factor kappaB activation through the binding between inhibitor of nuclear factor-kappaBalpha and the processed NH(2)-terminal region of Mig-6"، Cancer Res.، 62 (20): 5668–71، PMID 12384522.
- "Mitogen-inducible gene 6 (MIG-6), adipophilin and tuftelin are inducible by hypoxia"، FEBS Lett.، 530 (1–3): 186–190، 2002، doi:10.1016/S0014-5793(02)03475-0، PMID 12387890.
- Strausberg RL؛ Feingold EA؛ Grouse LH؛ وآخرون (2003)، "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences"، Proc. Natl. Acad. Sci. U.S.A.، 99 (26): 16899–16903، Bibcode:2002PNAS...9916899M، doi:10.1073/pnas.242603899، PMC 139241، PMID 12477932.
- Anastasi S؛ Fiorentino L؛ Fiorini M؛ وآخرون (2003)، "Feedback inhibition by RALT controls signal output by the ErbB network"، Oncogene، 22 (27): 4221–4234، doi:10.1038/sj.onc.1206516، PMID 12833145.
- Ota T؛ Suzuki Y؛ Nishikawa T؛ وآخرون (2004)، "Complete sequencing and characterization of 21,243 full-length human cDNAs"، Nat. Genet.، 36 (1): 40–45، doi:10.1038/ng1285، PMID 14702039.
- Gerhard DS؛ Wagner L؛ Feingold EA؛ وآخرون (2004)، "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)"، Genome Res.، 14 (10B): 2121–2127، doi:10.1101/gr.2596504، PMC 528928، PMID 15489334.
- "Gene 33 is an endogenous inhibitor of epidermal growth factor (EGF) receptor signaling and mediates dexamethasone-induced suppression of EGF function"، J. Biol. Chem.، 280 (4): 2924–2933، 2005، doi:10.1074/jbc.M408907200، PMID 15556944.
- "Modulation of Elk-dependent-transcription by Gene33"، J. Cell. Biochem.، 94 (6): 1190–1198، 2005، doi:10.1002/jcb.20370، PMID 15696545.
- Benzinger A؛ Muster N؛ Koch HB؛ وآخرون (2005)، "Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer"، Mol. Cell. Proteomics، 4 (6): 785–795، doi:10.1074/mcp.M500021-MCP200، PMID 15778465.
- Anastasi S؛ Sala G؛ Huiping C؛ وآخرون (2005)، "Loss of RALT/MIG-6 expression in ERBB2-amplified breast carcinomas enhances ErbB-2 oncogenic potency and favors resistance to Herceptin"، Oncogene، 24 (28): 4540–4548، doi:10.1038/sj.onc.1208658، PMID 15856022.
- Ballarò C؛ Ceccarelli S؛ Tiveron C؛ وآخرون (2006)، "Targeted expression of RALT in mouse skin inhibits epidermal growth factor receptor signalling and generates a Waved-like phenotype"، EMBO Rep.، 6 (8): 755–761، doi:10.1038/sj.embor.7400458، PMC 1369136، PMID 16007071.
- Gregory SG؛ Barlow KF؛ McLay KE؛ وآخرون (2006)، "The DNA sequence and biological annotation of human chromosome 1"، Nature، 441 (7091): 315–321، Bibcode:2006Natur.441..315G، doi:10.1038/nature04727، PMID 16710414.
- Zhang YW؛ Staal B؛ Su Y؛ وآخرون (2007)، "Evidence that MIG-6 is a tumor-suppressor gene"، Oncogene، 26 (2): 269–276، doi:10.1038/sj.onc.1209790، PMID 16819504.
بوابة طب
بوابة الكيمياء الحيوية
بوابة علم الأحياء الخلوي والجزيئي
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