GFI1
GFI1 (Growth factor independent 1 transcriptional repressor) هوَ بروتين يُشَفر بواسطة جين GFI1 في الإنسان.[1][2]
المراجع
- "Entrez Gene: GFI1 growth factor independent 1"، مؤرشف من الأصل في 08 مارس 2010.
- "Chromosomal localization of a gene, GF1, encoding a novel zinc finger protein reveals a new syntenic region between man and rodents"، Cytogenet Cell Genet، 70 (3–4): 263–7، يوليو 1995، doi:10.1159/000134048، PMID 7789186.
قراءة متعمقة
- "Progression of interleukin-2 (IL-2)-dependent rat T cell lymphoma lines to IL-2-independent growth following activation of a gene (Gfi-1) encoding a novel zinc finger protein"، Mol. Cell. Biol.، 13 (3): 1759–68، 1993، PMC 359488، PMID 8441411.
- "Gfi-1 encodes a nuclear zinc finger protein that binds DNA and functions as a transcriptional repressor"، Mol. Cell. Biol.، 16 (8): 4024–34، 1996، PMC 231398، PMID 8754800.
- "Cloning of the human Gfi-1 gene and its mapping to chromosome region 1p22"، Oncogene، 14 (8): 1003–5، 1997، doi:10.1038/sj.onc.1200910، PMID 9051000.
- "The zinc finger protein Gfi-1 can enhance STAT3 signaling by interacting with the STAT3 inhibitor PIAS3"، EMBO J.، 19 (21): 5845–55، 2000، doi:10.1093/emboj/19.21.5845، PMC 305799، PMID 11060035.
- "Erythroid expansion mediated by the Gfi-1B zinc finger protein: role in normal hematopoiesis"، Blood، 100 (8): 2769–77، 2002، doi:10.1182/blood-2002-01-0182، PMID 12351384.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences"، Proc. Natl. Acad. Sci. U.S.A.، 99 (26): 16899–903، 2003، doi:10.1073/pnas.242603899، PMC 139241، PMID 12477932.
- "Mutations in proto-oncogene GFI1 cause human neutropenia and target ELA2"، Nat. Genet.، 34 (3): 308–12، 2003، doi:10.1038/ng1170، PMC 2832179، PMID 12778173.
- "Gfi-1 attaches to the nuclear matrix, associates with ETO (MTG8) and histone deacetylase proteins, and represses transcription using a TSA-sensitive mechanism"، J. Cell. Biochem.، 89 (5): 1005–18، 2003، doi:10.1002/jcb.10548، PMID 12874834.
- "Targeted transcriptional repression of Gfi1 by GFI1 and GFI1B in lymphoid cells"، Nucleic Acids Res.، 32 (8): 2508–19، 2004، doi:10.1093/nar/gkh570، PMC 419458، PMID 15131254.
- "Identification of growth factor independent-1 (GFI1) as a repressor of 25-hydroxyvitamin D 1-alpha hydroxylase (CYP27B1) gene expression in human prostate cancer cells"، Endocr. Relat. Cancer، 12 (2): 351–65، 2005، doi:10.1677/erc.1.00920، PMID 15947108.
- "Gfi1 Coordinates Epigenetic Repression of p21Cip/WAF1 by Recruitment of Histone Lysine Methyltransferase G9a and Histone Deacetylase 1"، Mol. Cell. Biol.، 25 (23): 10338–51، 2005، doi:10.1128/MCB.25.23.10338-10351.2005، PMC 1291230، PMID 16287849.
- "Diminished proteasomal degradation results in accumulation of Gfi1 protein in monocytes"، Blood، 109 (1): 100–8، 2007، doi:10.1182/blood-2006-02-003590، PMID 16888099.
- "Role of oncoprotein growth factor independent-1 (GFI1) in repression of 25-hydroxyvitamin D 1alpha-hydroxylase (CYP27B1): a comparative analysis in human prostate cancer and kidney cells"، J. Steroid Biochem. Mol. Biol.، 103 (3–5): 742–6، 2007، doi:10.1016/j.jsbmb.2006.12.014، PMID 17207994.
- "Cooperative interaction between ETS1 and GFI1 transcription factors in the repression of Bax gene expression"، Oncogene، 26 (24): 3541–50، 2007، doi:10.1038/sj.onc.1210140، PMID 17213822.
- "Growth factor independence-1 (Gfi-1) plays a role in mediating specific granule deficiency (SGD) in a patient lacking a gene-inactivating mutation in the C/EBPϵ gene"، Blood، 109 (10): 4181–90، 2007، doi:10.1182/blood-2005-05-022004، PMC 1885490، PMID 17244686.
- "Gfi1 ubiquitination and proteasomal degradation is inhibited by the ubiquitin ligase Triad1"، Blood، 110 (9): 3128–35، 2007، doi:10.1182/blood-2006-11-058602، PMID 17646546.
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