CP-135807

CP-135807 is a drug which acts as a potent and selective agonist for the 5-HT1D serotonin receptor, and is used to study the function of this receptor subtype.[1][2]

CP-135807
Identifiers
IUPAC name
  • 3-([(2R)-1-methylpyrrolidin-2-yl]methyl)-N-(3-nitropyridin-2-yl)-1H-indol-5-amine
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.189.849
Chemical and physical data
FormulaC19H21N5O2
Molar mass351.410 g·mol−1
3D model (JSmol)
SMILES
  • CN1CCC[C@@H]1Cc2c[nH]c3c2cc(cc3)Nc4c(cccn4)[N+](=O)[O-]
InChI
  • InChI=1S/C19H21N5O2/c1-23-9-3-4-15(23)10-13-12-21-17-7-6-14(11-16(13)17)22-19-18(24(25)26)5-2-8-20-19/h2,5-8,11-12,15,21H,3-4,9-10H2,1H3,(H,20,22)/t15-/m1/s1
  • Key:YPFIYPNOWVPAPR-OAHLLOKOSA-N
  (verify)

See also

References
  1. Mansbach RS, Rovetti CC, Macor JE (December 1996). "CP-135,807, a selective 5-HT1D agonist: effects in drug discrimination and punishment procedures in the pigeon". Psychopharmacology. 128 (3): 313–9. doi:10.1007/s002130050139. PMID 8972551. S2CID 19376926.
  2. Hertel P, Nomikos GG, Svensson TH (August 1999). "The antipsychotic drug risperidone interacts with auto- and hetero-receptors regulating serotonin output in the rat frontal cortex". Neuropharmacology. 38 (8): 1175–84. doi:10.1016/S0028-3908(99)00045-3. PMID 10462130. S2CID 33060351.


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