Estradiol benzoate/progesterone/testosterone propionate

EB/P4/TP
Combination of
Estradiol benzoateEstrogen
ProgesteroneProgestogen
Testosterone propionateAndrogen; Anabolic steroid
Clinical data
Trade namesLukestra, Steratrin, Trihormonal, Trinestryl
Other namesEB/P4/TP
Routes of
administration		Intramuscular injection

Estradiol benzoate/progesterone/testosterone propionate (EB/P4/TP), sold under the brand names Lukestra, Steratrin, Trihormonal, and Trinestryl, is an injectable combination medication of estradiol benzoate (EB), an estrogen, progesterone (P4), a progestogen, and testosterone propionate (TP), an androgen/anabolic steroid.[1][2][3][4][5] It contained 1 to 3 mg EB, 20 to 25 mg P4, and 25 mg TP, was provided in the form of ampoules, and was administered by intramuscular injection.[1][2][3][4][6] The medication was introduced by 1949 and was marketed in the United States, the United Kingdom, and Germany among other places.[7][8][5] It is no longer available.[9][10]

See also

References

  1. 1 2 Nowakowski H (9 March 2013). Hormone und Psyche die Endokrinologie des Alternden Menschen: Fünftes Symposion der Deutschen Gesellschaft für Endokrinologie Freiburg (Breisgau), den 7. bis 9. März 1957. Springer-Verlag. pp. 55–. ISBN 978-3-642-87014-9.
  2. 1 2 Hager HH, Kern W, List PH, Roth HJ (29 July 2013). Hagers Handbuch der Pharmazeutischen Praxis: Für Apotheker, Arzneimittelhersteller, Ärzte und Medizinalbeamte: Wirkstoffgruppen II Chemikalien und Drogen (A-AL). Springer-Verlag. pp. 187–. ISBN 978-3-662-25655-8.
  3. 1 2 Walther K, Auterhoff H, Neuwald F, Schmid W (9 March 2013). Hagers Handbuch der Pharmazeutischen Praxis: Für Apotheker, Arzneimittelhersteller, Drogisten, Ärzte und Medizinalbeamte. Springer-Verlag. pp. 1163–. ISBN 978-3-642-49759-9.
  4. 1 2 Ufer J (1960). Hormontherapie in der Frauenheilkunde: Grundlagen und Praxis. de Gruyter. p. 155. ISBN 9783111138770.
  5. 1 2 Bishop PM (1962). Chemistry of the Sex Hormones. Thomas. p. 85. Lukestra Injection Steroid Triad (oestradiol benz., test. prop. and progesterone) Merck, Sharp & Dohme
  6. ↑ Greenblatt RB, Barfield WE (January 1952). "Hormonal control of functional uterine bleeding". Am. J. Obstet. Gynecol. 63 (1): 153–7. doi:10.1016/s0002-9378(16)38992-x. PMID 14894511. S2CID 6863371. The estrogen-progesterone-testosterone combinations used in our studies were supplied by the following pharmaceutical companies: Wyeth, Inc.: Tristerone (6 mg. estrone, 50 mg. progesterone, 25 mg. testosterone). Schering Corporation: Steratrin (1 mg. estradiol benzoate, 25 mg. progesterone, 25 mg. testoterone propionate).Sharp and Dohme, Inc.: Lukestra (1.66 mg. estradiol benzoate, 25 mg. progesterone, 25 mg. testosterone propionate).
  7. ↑ United States. Patent Office (1950). Official Gazette of the United States Patent Office. U.S. Patent Office. pp. 31–.
  8. ↑ Unlisted Drugs. Unlisted Drugs Committee of the Pharmaceutical Section, Science-Technology Group, Special Libraries Association. 1952. Lukestra C. each cc, contains: estradiol benzoate, 1.67 mg.; progesterone, 25 mg.; and testosterone propionate, 25 mg.
  9. ↑ "?". IBM Watson Health.
  10. ↑ "Estradiol". Drugs.com.



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