2-Oxo-PCE

2-Oxo-PCE (also known as N-ethyldeschloroketamine, eticyclidone and O-PCE) is a dissociative anesthetic of the arylcyclohexylamine class that is closely related to deschloroketamine and eticyclidine, and has been sold online as a designer drug.[4][5][6][7][8][9][10][11]

2-Oxo-PCE
Legal status
Legal status
  • CA: Schedule I[1]
  • DE: NpSG (Industrial and scientific use only)
  • UK: Class B
  • Illegal in Hong Kong[2] and Sweden[3]
Identifiers
IUPAC name
  • 2-(ethylamino)-2-phenyl-cyclohexanone
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC14H19NO
Molar mass217.312 g·mol−1
3D model (JSmol)
SMILES
  • CCNC1(CCCCC1=O)C2=CC=CC=C2
InChI
  • InChI=1S/C14H19NO/c1-2-15-14(11-7-6-10-13(14)16)12-8-4-3-5-9-12/h3-5,8-9,15H,2,6-7,10-11H2,1H3
  • Key:IDLSBAANXISGEI-UHFFFAOYSA-N

See also

References
  1. "Controlled Drugs and Substances Act (S.C. 1996, c. 19) - SCHEDULE I". Government of Canada - Justice Laws Website. Retrieved 15 July 2020.
  2. Cheng WC, Dao KL (April 2020). "The Emergence of Deschloro-N-ethyl-ketamine, a Ketamine Analog, in Drug Seizures and Drug Driving Cases in Hong Kong". Journal of Analytical Toxicology. 44 (8): 886–895. doi:10.1093/jat/bkaa038. PMID 32364605.
  3. "Fjorton nya ämnen klassas som narkotika eller hälsofarlig vara" (in Swedish). Folkhälsomyndigheten. 12 November 2018.
  4. "deschloro-N-ethyl-Ketamine (hydrochloride) (CAS 4551-92-2)". www.caymanchem.com.
  5. Wallach J, Brandt SD (September 2018). 1,2-Diarylethylamine- and Ketamine-Based New Psychoactive Substances. Handbook of Experimental Pharmacology. Vol. 252. Springer International Publishing. pp. 305–352. doi:10.1007/164_2018_148. ISBN 978-3-030-10561-7. PMID 30196446 – via Springer Link.
  6. Chong YK, Tang MH, Chan CL, Li YK, Ching CK, Mak TW (December 2017). "2-oxo-PCE: ketamine analogue on the streets". Hong Kong Medical Journal = Xianggang Yi Xue Za Zhi. 23 (6): 665–6. doi:10.12809/hkmj177089. PMID 29226843.
  7. Tang MH, Chong YK, Chan CY, Ching CK, Lai CK, Li YK, Mak TW (September 2018). "Cluster of acute poisonings associated with an emerging ketamine analogue, 2-oxo-PCE". Forensic Science International. 290: 238–243. doi:10.1016/j.forsciint.2018.07.014. PMID 30081327. S2CID 207558276.
  8. Tang MH, Hung LY, Lai CK, Ching CK, Mak TW (September 2018). "9-year review of new psychoactive substance use in Hong Kong: A clinical laboratory perspective". Hong Kong Journal of Emergency Medicine. 26 (3): 179–185. doi:10.1177/1024907918798553. ISSN 1024-9079.
  9. Li C, Lai CK, Tang MH, Chan CC, Chong YK, Mak TW (April 2019). "Ketamine analogues multiplying in Hong Kong". Hong Kong Medical Journal = Xianggang Yi Xue Za Zhi. 25 (2): 169. doi:10.12809/hkmj197863. PMID 30971512.
  10. Theofel N, Möller P, Vejmelka E, Kastner K, Roscher S, Scholtis S, Tsokos M (March 2019). "A Fatal Case Involving N-Ethyldeschloroketamine (2-Oxo-PCE) and Venlafaxine". Journal of Analytical Toxicology. 43 (2): e2–e6. doi:10.1093/jat/bky063. PMID 30365028.
  11. Tamama K, Lynch MJ (October 2019). "Newly Emerging Drugs of Abuse". Handbook of Experimental Pharmacology. 258: 463–502. doi:10.1007/164_2019_260. ISBN 978-3-030-33678-3. PMID 31595417. S2CID 203983418.
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