3-Methyl-PCP

3-Methyl-PCP (3'-Methyl-PCP, meta-Methyl-PCP, 3-Me-PCP) is a recreational designer drug with dissociative effects. It is an arylcyclohexylamine derivative, related to drugs such as 3'-MeO-PCP and 3'-Me-PCPy.[1][2] It was first synthesised in the 1960s,[3] but was only identified on the illicit market in Hungary in September 2020,[4] and was made illegal in Hungary in April 2021.[5]

3'-Me-PCP
Legal status
Legal status
Identifiers
IUPAC name
  • 1-[1-(3-methylphenyl)cyclohexyl]piperidine
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC18H27N
Molar mass257.421 g·mol−1
3D model (JSmol)
SMILES
  • CC1=CC(=CC=C1)C2(CCCCC2)N3CCCCC3
InChI
  • InChI=1S/C18H27N/c1-16-9-8-10-17(15-16)18(11-4-2-5-12-18)19-13-6-3-7-14-19/h8-10,15H,2-7,11-14H2,1H3
  • Key:BMFKUCGCXMDGBK-UHFFFAOYSA-N

See also

References
  1. Linders J, Furlano DC, Mattson MV, Jacobson AE, Rice KC (February 2010). "Synthesis and preliminary biochemical evaluation of novel derivatives of PCP". Letters in Drug Design & Discovery. 7 (2): 79–87. doi:10.2174/157018010790225813.
  2. Wallach J, De Paoli G, Adejare A, Brandt SD (2014). "Preparation and analytical characterization of 1-(1-phenylcyclohexyl)piperidine (PCP) and 1-(1-phenylcyclohexyl)pyrrolidine (PCPy) analogues". Drug Testing and Analysis. 6 (7–8): 633–50. doi:10.1002/dta.1468. PMID 23554350.
  3. Maddox VH, Godefroi EF, Parcell RF (March 1965). "The synthesis of phencyclidine and other 1-arylcyclohexylamines". Journal of Medicinal Chemistry. 8: 230–5. doi:10.1021/jm00326a019. PMID 14332667.
  4. Jankovic M (28 January 2021). "EU Early Warning System" (PDF). Der Koordinator für Psychiatrie, Sucht- und Drogenfragen und der Beauftragte für Sucht- und Drogenfragen der Stadt Wien.
  5. Minister for Human Capacities. "Amendment of Minister for Human Capacities Decree No 55/2014 of 30 December 2014 on substances or groups of compounds classified as new psychoactive substances, 2021/225/HU". European Commission.



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