Protokylol

Protokylol (Ventaire) is a β-adrenergic receptor agonist used as a bronchodilator in Europe and the United States.[1]

Protokylol
Clinical data
ATC code
  • none
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
IUPAC name
  • 4-[2-[[2-(1,3-Benzodioxol-5-yl)-1-methyl-ethyl]amino]-1-hydroxy-ethyl]benzene-1,2-diol
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
ECHA InfoCard100.004.778
Chemical and physical data
FormulaC18H21NO5
Molar mass331.368 g·mol−1
3D model (JSmol)
SMILES
  • O1c2ccc(cc2OC1)CC(NCC(O)c3ccc(O)c(O)c3)C

It is methylenedioxyphenyl-isoproterenol.

The Para-Methoxyamphetamine (PMA) analog is twice the potency as the tenamfetamine analog.[2]

References

  1. Swiss Pharmaceutical Society (2000). Index Nominum 2000: International Drug Directory (Book with CD-ROM). Boca Raton: Medpharm Scientific Publishers. ISBN 3-88763-075-0.
  2. Biel JH, Schwarz EG, Sprengeler EP, Leiser HA, Friedman HL (1954). "Bronchodilators, N-Substituted Derivatives of 1-(3',4'-Dihydroxyphenyl)-2-aminoethanol (Arterenol)". Journal of the American Chemical Society. 76 (12): 3149–3153. doi:10.1021/ja01641a010. ISSN 0002-7863.
  • "Protokylol". Drug Information Portal. U.S. National Library of Medicine.


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