IL1RAP
IL1RAP (Interleukin-1 receptor accessory protein) هوَ بروتين يُشَفر بواسطة جين IL1RAP في الإنسان.[1][2][2][3]
المراجع
- "The human gene encoding the interleukin-1 receptor accessory protein (IL1RAP) maps to chromosome 3q28 by fluorescence in situ hybridization and radiation hybrid mapping"، Genomics، 47 (2): 325–6، أبريل 1998، doi:10.1006/geno.1997.5113، PMID 9479509.
- "Entrez Gene: IL1RAP interleukin 1 receptor accessory protein"، مؤرشف من الأصل في 05 ديسمبر 2010.
- "The interleukin-1 receptor accessory protein (IL-1RAcP) is essential for IL-1-induced activation of interleukin-1 receptor-associated kinase (IRAK) and stress-activated protein kinases (SAP kinases)"، J Biol Chem، 272 (12): 7727–31، أبريل 1997، doi:10.1074/jbc.272.12.7727، PMID 9065432.
قراءة متعمقة
- "Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex"، J. Biol. Chem.، 270 (23): 13757–65، 1995، doi:10.1074/jbc.270.23.13757، PMID 7775431.
- "IL-1Rrp is a novel receptor-like molecule similar to the type I interleukin-1 receptor and its homologues T1/ST2 and IL-1R AcP"، J. Biol. Chem.، 271 (8): 3967–70، 1996، doi:10.1074/jbc.271.8.3967، PMID 8626725.
- "Recruitment of IRAK to the interleukin 1 receptor complex requires interleukin 1 receptor accessory protein"، Proc. Natl. Acad. Sci. U.S.A.، 94 (24): 12829–32، 1998، Bibcode:1997PNAS...9412829H، doi:10.1073/pnas.94.24.12829، PMC 24223، PMID 9371760.
- "IL-1 receptor accessory protein is an essential component of the IL-1 receptor"، J. Immunol.، 161 (10): 5614–20، 1998، PMID 9820540.
- "The type II IL-1 receptor interacts with the IL-1 receptor accessory protein: a novel mechanism of regulation of IL-1 responsiveness"، J. Immunol.، 161 (12): 6871–7، 1999، PMID 9862719.
- "Interleukin-1beta activates a short STAT-3 isoform in clonal insulin-secreting cells"، FEBS Lett.، 442 (1): 57–60، 1999، doi:10.1016/S0014-5793(98)01623-8، PMID 9923604.
- "Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kappaB p65/RelA subunit"، Mol. Cell. Biol.، 19 (7): 4798–805، 1999، PMC 84278، PMID 10373529.
- "IL-1 signaling cascade in liver cells and the involvement of a soluble form of the IL-1 receptor accessory protein"، J. Immunol.، 164 (10): 5277–86، 2000، doi:10.4049/jimmunol.164.10.5277، PMID 10799889.
- "Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor"، Nat. Cell Biol.، 2 (6): 346–51، 2000، doi:10.1038/35014038، PMID 10854325.
- "Interleukin-1 receptor accessory protein is constitutively expressed in human endometrium throughout the menstrual cycle"، Mol. Hum. Reprod.، 7 (4): 333–9، 2001، doi:10.1093/molehr/7.4.333، PMID 11279295.
- "Transactivation by the p65 subunit of NF-kappaB in response to interleukin-1 (IL-1) involves MyD88, IL-1 receptor-associated kinase 1, TRAF-6, and Rac1"، Mol. Cell. Biol.، 21 (14): 4544–52، 2001، doi:10.1128/MCB.21.14.4544-4552.2001، PMC 87113، PMID 11416133.
- "Identification of essential regions in the cytoplasmic tail of interleukin-1 receptor accessory protein critical for interleukin-1 signaling"، J. Biol. Chem.، 277 (19): 16456–63، 2002، doi:10.1074/jbc.M201000200، PMID 11880380.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences"، Proc. Natl. Acad. Sci. U.S.A.، 99 (26): 16899–903، 2003، Bibcode:2002PNAS...9916899M، doi:10.1073/pnas.242603899، PMC 139241، PMID 12477932.
- "A role for SHPS-1/SIRPalpha1 in IL-1beta- and TNFalpha-dependent signaling"، Oncogene، 21 (57): 8871–8، 2003، doi:10.1038/sj.onc.1206018، PMID 12483539.
- Smith DE؛ Hanna R؛ Della Friend؛ وآخرون (2003)، "The soluble form of IL-1 receptor accessory protein enhances the ability of soluble type II IL-1 receptor to inhibit IL-1 action"، Immunity، 18 (1): 87–96، doi:10.1016/S1074-7613(02)00514-9، PMID 12530978.
- "Characterization of a cascade of protein interactions initiated at the IL-1 receptor"، Biochem. Biophys. Res. Commun.، 303 (2): 525–31، 2003، doi:10.1016/S0006-291X(03)00385-1، PMID 12659850.
- "TIRP, a novel Toll/interleukin-1 receptor (TIR) domain-containing adapter protein involved in TIR signaling"، J. Biol. Chem.، 278 (27): 24526–32، 2003، doi:10.1074/jbc.M303451200، PMID 12721283.
- "Expression of alternatively spliced interleukin-1 receptor accessory protein mRNAs is differentially regulated during inflammation and apoptosis"، Cell. Signal.، 15 (8): 793–802، 2004، doi:10.1016/S0898-6568(03)00039-1، PMID 12781872.
- بوابة طب
- بوابة علم الأحياء الخلوي والجزيئي
- بوابة الكيمياء الحيوية
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