SEMA3B
SEMA3B (Semaphorin 3B) هوَ بروتين يُشَفر بواسطة جين SEMA3B في الإنسان.[1][2][3]
الوظيفة
المراجع
- "Human semaphorins A(V) and IV reside in the 3p21.3 small cell lung cancer deletion region and demonstrate distinct expression patterns"، Proceedings of the National Academy of Sciences of the United States of America، 93 (9): 4120–5، أبريل 1996، doi:10.1073/pnas.93.9.4120، PMC 39497، PMID 8633026.
- "Entrez Gene: SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B"، مؤرشف من الأصل في 8 مارس 2010.
- "Murine semaphorin D/collapsin is a member of a diverse gene family and creates domains inhibitory for axonal extension"، Neuron، 14 (5): 941–8، مايو 1995، doi:10.1016/0896-6273(95)90332-1، PMID 7748561.
قراءة متعمقة
- "Construction of a 600-kilobase cosmid clone contig and generation of a transcriptional map surrounding the lung cancer tumor suppressor gene (TSG) locus on human chromosome 3p21.3: progress toward the isolation of a lung cancer TSG"، Cancer Research، 56 (7): 1487–92، أبريل 1996، PMID 8603390.
- "Semaphorins A and E act as antagonists of neuropilin-1 and agonists of neuropilin-2 receptors"، Nature Neuroscience، 1 (6): 487–93، أكتوبر 1998، doi:10.1038/2203، PMID 10196546.
- "The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium"، Cancer Research، 60 (21): 6116–33، نوفمبر 2000، PMID 11085536.
- "Inhibition of lung cancer cell growth and induction of apoptosis after reexpression of 3p21.3 candidate tumor suppressor gene SEMA3B"، Proceedings of the National Academy of Sciences of the United States of America، 98 (24): 13954–9، نوفمبر 2001، doi:10.1073/pnas.231490898، PMC 61148، PMID 11717452.
- "Human Semaphorin 3B (SEMA3B) located at chromosome 3p21.3 suppresses tumor formation in an adenocarcinoma cell line"، Cancer Research، 62 (2): 542–6، يناير 2002، PMID 11809707.
- "Identification of semaphorin3B as a direct target of p53"، Neoplasia، 4 (1): 82–7، 2002، doi:10.1038/sj.neo.7900211، PMC 1503310، PMID 11922394.
- "Allelic loss on chromosome 3p21.3 and promoter hypermethylation of semaphorin 3B in non-small cell lung cancer"، Cancer Research، 63 (12): 3352–5، يونيو 2003، PMID 12810670.
- "Semaphorin 3B (SEMA3B) induces apoptosis in lung and breast cancer, whereas VEGF165 antagonizes this effect"، Proceedings of the National Academy of Sciences of the United States of America، 101 (31): 11432–7، أغسطس 2004، doi:10.1073/pnas.0403969101، PMC 509218، PMID 15273288.
- "The race associated allele of Semaphorin 3B (SEMA3B) T415I and its role in lung cancer in African-Americans and Latino-Americans"، Carcinogenesis، 26 (8): 1446–9، أغسطس 2005، doi:10.1093/carcin/bgi098، PMID 15831529.
- "High-resolution analysis of 3p deletion in neuroblastoma and differential methylation of the SEMA3B tumor suppressor gene"، Cancer Genetics and Cytogenetics، 174 (2): 100–10، أبريل 2007، doi:10.1016/j.cancergencyto.2006.11.017، PMID 17452250.
- بوابة طب
- بوابة الكيمياء الحيوية
- بوابة علم الأحياء الخلوي والجزيئي
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