GZMA
GZMA (Granzyme A) هوَ بروتين يُشَفر بواسطة جين GZMA في الإنسان.[1][2][3]
المراجع
- "Identification of granzyme A isolated from cytotoxic T-lymphocyte-granules as one of the proteases encoded by CTL-specific genes"، FEBS Lett، 208 (1): 84–8، ديسمبر 1986، doi:10.1016/0014-5793(86)81537-X، PMID 3533635.
- "Entrez Gene: GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)"، مؤرشف من الأصل في 05 ديسمبر 2010.
- "Characterization of three serine esterases isolated from human IL-2 activated killer cells"، J Immunol، 141 (9): 3142–7، نوفمبر 1988، PMID 3262682.
قراءة متعمقة
- "Granzyme A binding to target cell proteins. Granzyme A binds to and cleaves nucleolin in vitro"، J. Biol. Chem.، 266 (22): 14703–8، 1991، PMID 1860869.
- "Human cytotoxic lymphocyte tryptase. Its purification from granules and the characterization of inhibitor and substrate specificity"، J. Biol. Chem.، 263 (26): 13215–22، 1988، PMID 3047119.
- "Comparative molecular model building of two serine proteinases from cytotoxic T lymphocytes"، Proteins، 4 (3): 190–204، 1989، doi:10.1002/prot.340040306، PMID 3237717.
- "Cloning and chromosomal assignment of a human cDNA encoding a T cell- and natural killer cell-specific trypsin-like serine protease"، Proc. Natl. Acad. Sci. U.S.A.، 85 (4): 1184–8، 1988، doi:10.1073/pnas.85.4.1184، PMC 279731، PMID 3257574.
- "Characterization of granzymes A and B isolated from granules of cloned human cytotoxic T lymphocytes"، J. Immunol.، 141 (10): 3471–7، 1988، PMID 3263427.
- "Loss of cytotoxic T lymphocyte function in Chediak-Higashi syndrome arises from a secretory defect that prevents lytic granule exocytosis"، J. Immunol.، 154 (11): 6122–31، 1995، PMID 7751653.
- "Close co-localization of CD4 and a serine esterase tryptase TL2 on the cell-surface of human monocytoid and CD4+ lymphoid cells"، Biochem. Biophys. Res. Commun.، 201 (3): 1390–5، 1994، doi:10.1006/bbrc.1994.1857، PMID 7912927.
- "The human granzyme A (HFSP, CTLA3) gene maps to 5q11-q12 and defines a new locus of the serine protease superfamily"، Genomics، 18 (2): 401–3، 1994، doi:10.1006/geno.1993.1483، PMID 8288245.
- "Recombinant human granzyme A binds to two putative HLA-associated proteins and cleaves one of them"، Proc. Natl. Acad. Sci. U.S.A.، 94 (17): 9285–90، 1997، doi:10.1073/pnas.94.17.9285، PMC 23158، PMID 9256474.
- "Extracellular granzymes A and B in humans: detection of native species during CTL responses in vitro and in vivo"، J. Immunol.، 160 (7): 3610–6، 1998، PMID 9531325.
- "Granzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysis"، Proc. Natl. Acad. Sci. U.S.A.، 98 (10): 5746–51، 2001، doi:10.1073/pnas.101329598، PMC 33284، PMID 11331782.
- "Granzyme A activates an endoplasmic reticulum-associated caspase-independent nuclease to induce single-stranded DNA nicks"، J. Biol. Chem.، 276 (46): 43285–93، 2001، doi:10.1074/jbc.M108137200، PMID 11555662.
- "HMG2 Interacts with the Nucleosome Assembly Protein SET and Is a Target of the Cytotoxic T-Lymphocyte Protease Granzyme A"، Mol. Cell. Biol.، 22 (8): 2810–20، 2002، doi:10.1128/MCB.22.8.2810-2820.2002، PMC 133744، PMID 11909973.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences"، Proc. Natl. Acad. Sci. U.S.A.، 99 (26): 16899–903، 2003، doi:10.1073/pnas.242603899، PMC 139241، PMID 12477932.
- "Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A"، Nat. Immunol.، 4 (2): 145–53، 2003، doi:10.1038/ni885، PMID 12524539.
- "Granzyme A: the road less traveled"، Nat. Immunol.، 4 (2): 106–8، 2003، doi:10.1038/ni0203-106، PMID 12555094.
- "Catalog of 680 variations among eight cytochrome p450 ( CYP) genes, nine esterase genes, and two other genes in the Japanese population"، J. Hum. Genet.، 48 (5): 249–70، 2003، doi:10.1007/s10038-003-0021-7، PMID 12721789.
- "The oligomeric structure of human granzyme A is a determinant of its extended substrate specificity"، Nat. Struct. Biol.، 10 (7): 527–34، 2003، doi:10.1038/nsb944، PMID 12819769.
بوابة الكيمياء الحيوية
بوابة طب
بوابة علم الأحياء
بوابة علم الأحياء الخلوي والجزيئي
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