BTNL2

BTNL2
المعرفات
الأسماء المستعارة	BTNL2, BTL-II, BTN7, HSBLMHC1, SS2, butyrophilin like 2
معرفات خارجية	الوراثة المندلية البشرية عبر الإنترنت 606000 MGI: MGI:1859549 HomoloGene: 10482 GeneCards: 56244
علم الوجود الجيني
الوظيفة الجزيئية	• signaling receptor binding;
المكونات الخلوية	• غشاء; • مكون تكاملي للغشاء; • غشاء خلوي; • external side of plasma membrane;
العمليات الحيوية	• regulation of immune response; • T cell receptor signaling pathway;
	المصادر:Amigo / QuickGO
نمط التعبير عن الحمض النووي الريبوزي
	المزيد من بيانات التعبير المرجعية
أورثولوج
	Q9UIR0
	O70355
	‏NM_019602 NM_001304561، ‏NM_019602
	‏XM_006524645، ‏XM_006524646، ‏XM_017317579 NM_079835، ‏XM_006524645، ‏XM_006524646، ‏XM_017317579
	‏XP_016866546 NP_001291490، ‏XP_016866546
	‏XP_006524708، ‏XP_006524709، ‏XP_017173068 NP_524574، ‏XP_006524708، ‏XP_006524709، ‏XP_017173068
	ويكي بيانات
اعرض/عدّل إنسان	اعرض/عدّل فأر

BTNL2‏ (Butyrophilin like 2) هوَ بروتين يُشَفر بواسطة جين BTNL2 في الإنسان.[1][2][3][4]

المراجع

"BTL-II: a polymorphic locus with homology to the butyrophilin gene family, located at the border of the major histocompatibility complex class II and class III regions in human and mouse"، Immunogenetics، 51 (4–5): 373–82، مايو 2000، doi:10.1007/s002510050633، PMID 10803852.
Pagani, Luca؛ Lawson, Daniel John؛ Jagoda, Evelyn؛ Mörseburg, Alexander؛ Eriksson, Anders؛ Mitt, Mario؛ Clemente, Florian؛ Hudjashov, Georgi؛ DeGiorgio, Michael؛ Saag, Lauri؛ Wall, Jeffrey D.؛ Cardona, Alexia؛ Mägi, Reedik؛ Sayres, Melissa A. Wilson؛ Kaewert, Sarah؛ Inchley, Charlotte؛ Scheib, Christiana L.؛ Järve, Mari؛ Karmin, Monika؛ Jacobs, Guy S.؛ Antao, Tiago؛ Iliescu, Florin Mircea؛ Kushniarevich, Alena؛ Ayub, Qasim؛ Tyler-Smith, Chris؛ Xue, Yali؛ Yunusbayev, Bayazit؛ Tambets, Kristiina؛ Mallick, Chandana Basu؛ Saag, Lehti؛ Pocheshkhova, Elvira؛ Andriadze, George؛ Muller, Craig؛ Westaway, Michael C.؛ Lambert, David M.؛ Zoraqi, Grigor؛ Turdikulova, Shahlo؛ Dalimova, Dilbar؛ Sabitov, Zhaxylyk؛ Sultana, Gazi Nurun Nahar؛ Lachance, Joseph؛ Tishkoff, Sarah؛ Momynaliev, Kuvat؛ Isakova, Jainagul؛ Damba, Larisa D.؛ Gubina, Marina؛ Nymadawa, Pagbajabyn؛ Evseeva, Irina؛ Atramentova, Lubov؛ Utevska, Olga؛ Ricaut, François-Xavier؛ Brucato, Nicolas؛ Sudoyo, Herawati؛ Letellier, Thierry؛ Cox, Murray P.؛ Barashkov, Nikolay A.؛ Škaro, Vedrana؛ Mulahasanovic´, Lejla؛ Primorac, Dragan؛ Sahakyan, Hovhannes؛ Mormina, Maru؛ Eichstaedt, Christina A.؛ Lichman, Daria V.؛ Abdullah, Syafiq؛ Chaubey, Gyaneshwer؛ Wee, Joseph T. S.؛ Mihailov, Evelin؛ Karunas, Alexandra؛ Litvinov, Sergei؛ Khusainova, Rita؛ Ekomasova, Natalya؛ Akhmetova, Vita؛ Khidiyatova, Irina؛ Marjanović, Damir؛ Yepiskoposyan, Levon؛ Behar, Doron M.؛ Balanovska, Elena؛ Metspalu, Andres؛ Derenko, Miroslava؛ Malyarchuk, Boris؛ Voevoda, Mikhail؛ Fedorova, Sardana A.؛ Osipova, Ludmila P.؛ Lahr, Marta Mirazón؛ Gerbault, Pascale؛ Leavesley, Matthew؛ Migliano, Andrea Bamberg؛ Petraglia, Michael؛ Balanovsky, Oleg؛ Khusnutdinova, Elza K.؛ Metspalu, Ene؛ Thomas, Mark G.؛ Manica, Andrea؛ Nielsen, Rasmus؛ Villems, Richard؛ Willerslev, Eske؛ Kivisild, Toomas؛ Metspalu, Mait (21 سبتمبر 2016)، "Genomic analyses inform on migration events during the peopling of Eurasia"، Nature، 538 (7624): 238–242، doi:10.1038/nature19792، PMC 5164938.
"Sarcoidosis is associated with a truncating splice site mutation in BTNL2"، Nat Genet، 37 (4): 357–64، مارس 2005، doi:10.1038/ng1519، PMID 15735647.
"Entrez Gene: BTNL2 butyrophilin-like 2 (MHC class II associated)"، مؤرشف من الأصل في 05 ديسمبر 2010.

قراءة متعمقة

"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences"، Proc. Natl. Acad. Sci. U.S.A.، 99 (26): 16899–903، 2003، doi:10.1073/pnas.242603899، PMC 139241، PMID 12477932.
"The DNA sequence and analysis of human chromosome 6"، Nature، 425 (6960): 805–11، 2003، doi:10.1038/nature02055، PMID 14574404.
"Widespread occurrence of alternative splicing at NAGNAG acceptors contributes to proteome plasticity"، Nat. Genet.، 36 (12): 1255–7، 2005، doi:10.1038/ng1469، PMID 15516930.
"The BTNL2 gene and sarcoidosis susceptibility in African Americans and Whites"، Am. J. Hum. Genet.، 77 (3): 491–9، 2006، doi:10.1086/444435، PMC 1226214، PMID 16080124.
"Association of the truncating splice site mutation in BTNL2 with multiple sclerosis is secondary to HLA-DRB1*15"، Hum. Mol. Genet.، 15 (1): 155–61، 2006، doi:10.1093/hmg/ddi436، PMID 16321988.
"Analysis of a functional BTNL2 polymorphism in type 1 diabetes, rheumatoid arthritis, and systemic lupus erythematosus"، Hum. Immunol.، 66 (12): 1235–41، 2006، doi:10.1016/j.humimm.2006.02.003، PMID 16690410.
"Expression of receptor for advanced glycation end products in sarcoid granulomas"، Am. J. Respir. Crit. Care Med.، 175 (5): 498–506، 2007، doi:10.1164/rccm.200601-136OC، PMID 17170388.
"BTNL2, a butyrophilin/B7-like molecule, is a negative costimulatory molecule modulated in intestinal inflammation"، J. Immunol.، 178 (3): 1523–33، 2007، doi:10.4049/jimmunol.178.3.1523، PMID 17237401.
"Allelic variation in BTNL2 and susceptibility to tuberculosis in a South African population"، Microbes Infect.، 9 (4): 522–8، 2007، doi:10.1016/j.micinf.2007.01.011، PMID 17347014.
"Analysis of the BTNL2 truncating splice site mutation in tuberculosis, leprosy and Crohn's disease"، Tissue Antigens، 69 (3): 236–41، 2007، doi:10.1111/j.1399-0039.2006.00795.x، PMID 17493147.
"Butyrophilin-like 2 gene is associated with ulcerative colitis in the Japanese under strong linkage disequilibrium with HLA-DRB1*1502"، Tissue Antigens، 70 (2): 128–35، 2007، doi:10.1111/j.1399-0039.2007.00866.x، PMID 17610417.
"Analysis of BTNL2 genetic polymorphisms in British and Dutch patients with sarcoidosis"، Tissue Antigens، 70 (3): 219–27، 2007، doi:10.1111/j.1399-0039.2007.00879.x، PMID 17661910.

بوابة علم الأحياء الخلوي والجزيئي
بوابة طب
بوابة الكيمياء الحيوية

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[pmid10803852-1] "BTL-II: a polymorphic locus with homology to the butyrophilin gene family, located at the border of the major histocompatibility complex class II and class III regions in human and mouse"، Immunogenetics، 51 (4–5): 373–82، مايو 2000، doi:10.1007/s002510050633، PMID 10803852.

[2] Pagani, Luca؛ Lawson, Daniel John؛ Jagoda, Evelyn؛ Mörseburg, Alexander؛ Eriksson, Anders؛ Mitt, Mario؛ Clemente, Florian؛ Hudjashov, Georgi؛ DeGiorgio, Michael؛ Saag, Lauri؛ Wall, Jeffrey D.؛ Cardona, Alexia؛ Mägi, Reedik؛ Sayres, Melissa A. Wilson؛ Kaewert, Sarah؛ Inchley, Charlotte؛ Scheib, Christiana L.؛ Järve, Mari؛ Karmin, Monika؛ Jacobs, Guy S.؛ Antao, Tiago؛ Iliescu, Florin Mircea؛ Kushniarevich, Alena؛ Ayub, Qasim؛ Tyler-Smith, Chris؛ Xue, Yali؛ Yunusbayev, Bayazit؛ Tambets, Kristiina؛ Mallick, Chandana Basu؛ Saag, Lehti؛ Pocheshkhova, Elvira؛ Andriadze, George؛ Muller, Craig؛ Westaway, Michael C.؛ Lambert, David M.؛ Zoraqi, Grigor؛ Turdikulova, Shahlo؛ Dalimova, Dilbar؛ Sabitov, Zhaxylyk؛ Sultana, Gazi Nurun Nahar؛ Lachance, Joseph؛ Tishkoff, Sarah؛ Momynaliev, Kuvat؛ Isakova, Jainagul؛ Damba, Larisa D.؛ Gubina, Marina؛ Nymadawa, Pagbajabyn؛ Evseeva, Irina؛ Atramentova, Lubov؛ Utevska, Olga؛ Ricaut, François-Xavier؛ Brucato, Nicolas؛ Sudoyo, Herawati؛ Letellier, Thierry؛ Cox, Murray P.؛ Barashkov, Nikolay A.؛ Škaro, Vedrana؛ Mulahasanovic´, Lejla؛ Primorac, Dragan؛ Sahakyan, Hovhannes؛ Mormina, Maru؛ Eichstaedt, Christina A.؛ Lichman, Daria V.؛ Abdullah, Syafiq؛ Chaubey, Gyaneshwer؛ Wee, Joseph T. S.؛ Mihailov, Evelin؛ Karunas, Alexandra؛ Litvinov, Sergei؛ Khusainova, Rita؛ Ekomasova, Natalya؛ Akhmetova, Vita؛ Khidiyatova, Irina؛ Marjanović, Damir؛ Yepiskoposyan, Levon؛ Behar, Doron M.؛ Balanovska, Elena؛ Metspalu, Andres؛ Derenko, Miroslava؛ Malyarchuk, Boris؛ Voevoda, Mikhail؛ Fedorova, Sardana A.؛ Osipova, Ludmila P.؛ Lahr, Marta Mirazón؛ Gerbault, Pascale؛ Leavesley, Matthew؛ Migliano, Andrea Bamberg؛ Petraglia, Michael؛ Balanovsky, Oleg؛ Khusnutdinova, Elza K.؛ Metspalu, Ene؛ Thomas, Mark G.؛ Manica, Andrea؛ Nielsen, Rasmus؛ Villems, Richard؛ Willerslev, Eske؛ Kivisild, Toomas؛ Metspalu, Mait (21 سبتمبر 2016)، "Genomic analyses inform on migration events during the peopling of Eurasia"، Nature، 538 (7624): 238–242، doi:10.1038/nature19792، PMC 5164938.

[pmid15735647-3] "Sarcoidosis is associated with a truncating splice site mutation in BTNL2"، Nat Genet، 37 (4): 357–64، مارس 2005، doi:10.1038/ng1519، PMID 15735647.

[entrez-4] "Entrez Gene: BTNL2 butyrophilin-like 2 (MHC class II associated)"، مؤرشف من الأصل في 05 ديسمبر 2010.