HEY2
HEY2 (Hes related family bHLH transcription factor with YRPW motif 2) هوَ بروتين يُشَفر بواسطة جين HEY2 في الإنسان.[1][2]
المراجع
- "Hey genes: a novel subfamily of hairy- and Enhancer of split related genes specifically expressed during mouse embryogenesis"، Mech. Dev.، 85 (1–2): 173–7، سبتمبر 1999، doi:10.1016/S0925-4773(99)00080-5، PMID 10415358.
- "Entrez Gene: HEY2 hairy/enhancer-of-split related with YRPW motif 2"، مؤرشف من الأصل في 05 ديسمبر 2010.
قراءة متعمقة
- "HES and HERP families: multiple effectors of the Notch signaling pathway"، J. Cell. Physiol.، 194 (3): 237–55، 2003، doi:10.1002/jcp.10208، PMID 12548545.
- "Hesr, a mediator of the Notch signaling, functions in heart and vessel development"، Trends Cardiovasc. Med.، 15 (5): 190–4، 2005، doi:10.1016/j.tcm.2005.05.005، PMID 16165016.
- "Cardiovascular basic helix loop helix factor 1, a novel transcriptional repressor expressed preferentially in the developing and adult cardiovascular system"، J. Biol. Chem.، 275 (9): 6381–7، 2000، doi:10.1074/jbc.275.9.6381، PMID 10692439.
- "gridlock, an HLH gene required for assembly of the aorta in zebrafish"، Science، 287 (5459): 1820–4، 2000، doi:10.1126/science.287.5459.1820، PMID 10710309.
- "Characterization of the human and mouse HEY1, HEY2, and HEYL genes: cloning, mapping, and mutation screening of a new bHLH gene family"، Genomics، 66 (2): 195–203، 2000، doi:10.1006/geno.2000.6200، PMID 10860664.
- "The basic helix-loop-helix transcription factors dHAND and eHAND exhibit dimerization characteristics that suggest complex regulation of function"، J. Biol. Chem.، 275 (43): 33567–73، 2000، doi:10.1074/jbc.M005888200، PMC 2561327، PMID 10924525.
- "Members of the HRT family of basic helix-loop-helix proteins act as transcriptional repressors downstream of Notch signaling"، Proc. Natl. Acad. Sci. U.S.A.، 97 (25): 13655–60، 2000، doi:10.1073/pnas.250485597، PMC 17631، PMID 11095750.
- "HERP, a new primary target of Notch regulated by ligand binding"، Mol. Cell. Biol.، 21 (17): 6071–9، 2001، doi:10.1128/MCB.21.17.6071-6079.2001، PMC 87324، PMID 11486044.
- "HERP, a novel heterodimer partner of HES/E(spl) in Notch signaling"، Mol. Cell. Biol.، 21 (17): 6080–9، 2001، doi:10.1128/MCB.21.17.6080-6089.2001، PMC 87325، PMID 11486045.
- "Human Sir2-related protein SIRT1 associates with the bHLH repressors HES1 and HEY2 and is involved in HES1- and HEY2-mediated transcriptional repression"، Biochem. Biophys. Res. Commun.، 301 (1): 250–7، 2003، doi:10.1016/S0006-291X(02)03020-6، PMID 12535671.
- "Phenotypic variability in Hey2 -/- mice and absence of HEY2 mutations in patients with congenital heart defects or Alagille syndrome"، Mamm. Genome، 15 (9): 711–6، 2004، doi:10.1007/s00335-004-2389-x، PMID 15389319.
- "Mouse hesr1 and hesr2 genes are redundantly required to mediate Notch signaling in the developing cardiovascular system"، Dev. Biol.، 278 (2): 301–9، 2005، doi:10.1016/j.ydbio.2004.10.025، PMID 15680351.
- "HERP1 inhibits myocardin-induced vascular smooth muscle cell differentiation by interfering with SRF binding to CArG box"، Arterioscler. Thromb. Vasc. Biol.، 25 (11): 2328–34، 2005، doi:10.1161/01.ATV.0000185829.47163.32، PMID 16151017.
- "Towards a proteome-scale map of the human protein-protein interaction network"، Nature، 437 (7062): 1173–8، 2005، doi:10.1038/nature04209، PMID 16189514.
- بوابة طب
- بوابة الكيمياء الحيوية
- بوابة علم الأحياء الخلوي والجزيئي
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