CD2AP
CD2AP (CD2 associated protein) هوَ بروتين يُشَفر بواسطة جين CD2AP في الإنسان.[1][2]
الوظيفة
المراجع
- "CMS: An adapter molecule involved in cytoskeletal rearrangements"، Proc Natl Acad Sci USA، 96 (11): 6211–6، يونيو 1999، doi:10.1073/pnas.96.11.6211، PMC 26861، PMID 10339567.
- "Entrez Gene: CD2AP CD2-associated protein"، مؤرشف من الأصل في 8 مارس 2010.
قراءة متعمقة
- "Normalization and subtraction: two approaches to facilitate gene discovery"، Genome Res.، 6 (9): 791–806، 1997، doi:10.1101/gr.6.9.791، PMID 8889548.
- "A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts"، Cell، 94 (5): 667–77، 1998، doi:10.1016/S0092-8674(00)81608-6، PMID 9741631، مؤرشف من الأصل في 20 ديسمبر 2017.
- "In vivo interaction of the adapter protein CD2-associated protein with the type 2 polycystic kidney disease protein, polycystin-2"، J. Biol. Chem.، 275 (42): 32888–93، 2000، doi:10.1074/jbc.M006624200، PMID 10913159.
- "CD2AP is expressed with nephrin in developing podocytes and is found widely in mature kidney and elsewhere"، Am. J. Physiol. Renal Physiol.، 279 (4): F785–92، 2000، PMID 10997929.
- "The adapter type protein CMS/CD2AP binds to the proto-oncogenic protein c-Cbl through a tyrosine phosphorylation-regulated Src homology 3 domain interaction"، J. Biol. Chem.، 276 (7): 4957–63، 2001، doi:10.1074/jbc.M005784200، PMID 11067845.
- "Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin"، J. Clin. Invest.، 108 (11): 1621–9، 2002، doi:10.1172/JCI12849، PMC 200981، PMID 11733557.
- "Identification of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASP), WASP-interacting protein (WIP), and ELMO1"، J. Biol. Chem.، 277 (31): 28238–46، 2002، doi:10.1074/jbc.M202783200، PMID 12029088.
- "The Wiskott-Aldrich syndrome protein acts downstream of CD2 and the CD2AP and PSTPIP1 adaptors to promote formation of the immunological synapse"، Immunity، 18 (1): 141–54، 2003، doi:10.1016/S1074-7613(02)00516-2، PMID 12530983.
- "CD2AP/CMS regulates endosome morphology and traffic to the degradative pathway through its interaction with Rab4 and c-Cbl"، Traffic، 4 (2): 97–112، 2003، doi:10.1034/j.1600-0854.2003.40205.x، PMID 12559036.
- "A Cortactin-CD2-associated protein (CD2AP) complex provides a novel link between epidermal growth factor receptor endocytosis and the actin cytoskeleton"، J. Biol. Chem.، 278 (24): 21805–13، 2003، doi:10.1074/jbc.M211407200، PMID 12672817.
- "Linking the T cell surface protein CD2 to the actin-capping protein CAPZ via CMS and CIN85"، J. Biol. Chem.، 278 (25): 22396–403، 2003، doi:10.1074/jbc.M302540200، PMID 12690097.
- "CD2-associated protein haploinsufficiency is linked to glomerular disease susceptibility"، Science، 300 (5623): 1298–300، 2003، doi:10.1126/science.1081068، PMID 12764198.
- "A novel proteomic screen for peptide-protein interactions"، J. Biol. Chem.، 279 (11): 10756–64، 2004، doi:10.1074/jbc.M309909200، PMID 14679214.
- "Recruitment of Pyk2 and Cbl to lipid rafts mediates signals important for actin reorganization in growing neurites"، J. Cell Sci.، 117 (Pt 12): 2557–68، 2004، doi:10.1242/jcs.01148، PMID 15128873.
- "Nephrin Forms a Complex with Adherens Junction Proteins and CASK in Podocytes and in Madin-Darby Canine Kidney Cells Expressing Nephrin"، Am. J. Pathol.، 165 (3): 923–36، 2004، doi:10.1016/S0002-9440(10)63354-8، PMC 1618613، PMID 15331416.
- "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells"، Nat. Biotechnol.، 23 (1): 94–101، 2005، doi:10.1038/nbt1046، PMID 15592455.
- "Nephrotic plasma alters slit diaphragm-dependent signaling and translocates nephrin, Podocin, and CD2 associated protein in cultured human podocytes"، J. Am. Soc. Nephrol.، 16 (3): 629–37، 2005، doi:10.1681/ASN.2004030172، PMID 15659563.
- بوابة طب
- بوابة الكيمياء الحيوية
- بوابة علم الأحياء الخلوي والجزيئي
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