Amitriptyline/chlordiazepoxide
Amitriptyline/chlordiazepoxide, sold under the brand names Limbitrol and Limbitrol DS, is a combination of amitriptyline (Elavil), a tricyclic antidepressant, and chlordiazepoxide (Librium), a benzodiazepine, which is approved for the treatment of moderate to severe depression associated with moderate to severe anxiety in the United States.[1][2] It contains 12.5 to 25 mg amitriptyline and 5 to 10 mg chlordiazepoxide per tablet.[1][2]
Combination of | |
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Amitriptyline | Tricyclic antidepressant |
Chlordiazepoxide | Benzodiazepine |
Clinical data | |
Trade names | Limbitrol, Limbitrol DS |
Routes of administration | Oral |
Legal status | |
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References
- Mylan Pharmaceuticals Inc. (May 2014). "Chlordiazepoxide and Amitriptyline Tablets Label" (PDF). U.S. Food and Drug Administration.
- Townsend MC, Morgan KI (9 January 2018). Pocket Guide to Psychiatric Nursing. F.A. Davis. pp. 443–. ISBN 978-0-8036-7705-0. OCLC 1019871725.
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GABAAR PAMs |
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Gabapentinoids (α2δ VDCC blockers) | |
Antidepressants |
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Sympatholytics (Antiadrenergics) |
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Antidepressants (TCAs and TeCAs) |
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Antihistamines |
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Antipsychotics |
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Anticonvulsants | |
Others |
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1,4-Benzodiazepines |
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1,5-Benzodiazepines | |
2,3-Benzodiazepines* |
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Triazolobenzodiazepines | |
Imidazobenzodiazepines | |
Oxazolobenzodiazepines | |
Thienodiazepines | |
Thienotriazolodiazepines | |
Thienobenzodiazepines* | |
Pyridodiazepines | |
Pyridotriazolodiazepines | |
Pyrazolodiazepines | |
Pyrrolodiazepines | |
Tetrahydroisoquinobenzodiazepines | |
Pyrrolobenzodiazepines* | |
Benzodiazepine prodrugs | |
* atypical activity profile (not GABAA receptor ligands) |
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