DRAP1
DRAP1 (DR1 associated protein 1) هوَ بروتين يُشَفر بواسطة جين DRAP1 في الإنسان.[1][2][2]
الوظيفة
المراجع
- "Requirement of a corepressor for Dr1-mediated repression of transcription"، Genes Dev، 10 (8): 1033–48، مايو 1996، doi:10.1101/gad.10.8.1033، PMID 8608938.
- "Entrez Gene: DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)"، مؤرشف من الأصل في 05 ديسمبر 2010.
قراءة متعمقة
- "A mechanism for repression of class II gene transcription through specific binding of NC2 to TBP-promoter complexes via heterodimeric histone fold domains."، EMBO J.، 15 (12): 3105–16، 1996، PMC 450253، PMID 8670811.
- "Functional dissection of a human Dr1-DRAP1 repressor complex."، Mol. Cell. Biol.، 17 (1): 36–45، 1997، PMC 231727، PMID 8972183.
- "Involvement of negative cofactor NC2 in active repression by zinc finger-homeodomain transcription factor AREB6."، Mol. Cell. Biol.، 18 (1): 10–8، 1998، doi:10.1128/mcb.18.1.10، PMC 121442، PMID 9418848.
- "The C-terminal domain-phosphorylated IIO form of RNA polymerase II is associated with the transcription repressor NC2 (Dr1/DRAP1) and is required for transcription activation in human nuclear extracts."، Proc. Natl. Acad. Sci. U.S.A.، 97 (13): 7184–9، 2000، Bibcode:2000PNAS...97.7184C، doi:10.1073/pnas.140202297، PMC 16520، PMID 10852970.
- "Crystal structure of negative cofactor 2 recognizing the TBP-DNA transcription complex."، Cell، 106 (1): 71–81، 2001، doi:10.1016/S0092-8674(01)00417-2، PMID 11461703.
- "Inhibition of excess nodal signaling during mouse gastrulation by the transcriptional corepressor DRAP1."، Science، 298 (5600): 1996–9، 2003، Bibcode:2002Sci...298.1996I، doi:10.1126/science.1073405، PMID 12471260.
- "Hypoxia actively represses transcription by inducing negative cofactor 2 (Dr1/DrAP1) and blocking preinitiation complex assembly."، J. Biol. Chem.، 278 (8): 5744–9، 2003، doi:10.1074/jbc.M212534200، PMID 12477712.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences."، Proc. Natl. Acad. Sci. U.S.A.، 99 (26): 16899–903، 2003، Bibcode:2002PNAS...9916899M، doi:10.1073/pnas.242603899، PMC 139241، PMID 12477932.
- "hLodestar/HuF2 interacts with CDC5L and is involved in pre-mRNA splicing."، Biochem. Biophys. Res. Commun.، 308 (4): 793–801، 2003، doi:10.1016/S0006-291X(03)01486-4، PMID 12927788.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."، Genome Res.، 14 (10B): 2121–7، 2004، doi:10.1101/gr.2596504، PMC 528928، PMID 15489334.
- "NC2alpha interacts with BTAF1 and stimulates its ATP-dependent association with TATA-binding protein."، Mol. Cell. Biol.، 24 (22): 10072–82، 2004، doi:10.1128/MCB.24.22.10072-10082.2004، PMC 525489، PMID 15509807.
- "Functional characterization of core promoter elements: DPE-specific transcription requires the protein kinase CK2 and the PC4 coactivator."، Mol. Cell، 18 (4): 471–81، 2005، doi:10.1016/j.molcel.2005.04.005، PMID 15893730.
- "A human protein-protein interaction network: a resource for annotating the proteome."، Cell، 122 (6): 957–68، 2005، doi:10.1016/j.cell.2005.08.029، PMID 16169070.
- "Towards a proteome-scale map of the human protein-protein interaction network."، Nature، 437 (7062): 1173–8، 2005، Bibcode:2005Natur.437.1173R، doi:10.1038/nature04209، PMID 16189514.
- "FEZ1 dimerization and interaction with transcription regulatory proteins involves its coiled-coil region."، J. Biol. Chem.، 281 (15): 9869–81، 2006، doi:10.1074/jbc.M513280200، PMID 16484223.
- "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration."، Cell، 125 (4): 801–14، 2006، doi:10.1016/j.cell.2006.03.032، PMID 16713569.
- "Global distribution of negative cofactor 2 subunit-alpha on human promoters."، Proc. Natl. Acad. Sci. U.S.A.، 104 (24): 10000–5، 2007، Bibcode:2007PNAS..10410000A، doi:10.1073/pnas.0703490104، PMC 1891239، PMID 17548813.
بوابة علم الأحياء الخلوي والجزيئي
بوابة طب
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