PHOX2A
PHOX2A (Paired like homeobox 2a) هوَ بروتين يُشَفر بواسطة جين PHOX2A في الإنسان.[1][2][3]
المراجع
- "Entrez Gene: PHOX2A paired-like (aristaless) homeobox 2a"، مؤرشف من الأصل في 05 ديسمبر 2010.
- "Homozygous mutations in ARIX(PHOX2A) result in congenital fibrosis of the extraocular muscles type 2"، Nat. Genet.، 29 (3): 315–20، نوفمبر 2001، doi:10.1038/ng744، PMID 11600883.
- "Mapping of the ARIX homeodomain gene to mouse chromosome 7 and human chromosome 11q13"، Genomics، 33 (3): 527–31، سبتمبر 1996، doi:10.1006/geno.1996.0230، PMID 8661014.
قراءة متعمقة
- "Phox2 genes - from patterning to connectivity"، Curr. Opin. Genet. Dev.، 12 (4): 435–40، 2002، doi:10.1016/S0959-437X(02)00322-2، PMID 12100889.
- "A 5.5-Mb high-resolution integrated map of distal 11q13"، Genomics، 39 (3): 340–7، 1997، doi:10.1006/geno.1996.4460، PMID 9119371.
- "The homeodomain protein Arix interacts synergistically with cyclic AMP to regulate expression of neurotransmitter biosynthetic genes"، J. Biol. Chem.، 272 (43): 27382–92، 1997، doi:10.1074/jbc.272.43.27382، PMID 9341190.
- "Congenital fibrosis of the extraocular muscles type 2, an inherited exotropic strabismus fixus, maps to distal 11q13"، Am. J. Hum. Genet.، 63 (2): 517–25، 1998، doi:10.1086/301980، PMC 1377321، PMID 9683611.
- "The homeodomain protein Arix promotes protein kinase A-dependent activation of the dopamine beta-hydroxylase promoter through multiple elements and interaction with the coactivator cAMP-response element-binding protein-binding protein"، J. Biol. Chem.، 275 (4): 2911–23، 2000، doi:10.1074/jbc.275.4.2911، PMID 10644760.
- "Sp proteins and Phox2b regulate the expression of the human Phox2a gene"، J. Neurosci.، 21 (18): 7037–45، 2001، PMID 11549713.
- "Mutations in the human ortholog of Aristaless cause X-linked mental retardation and epilepsy"، Nat. Genet.، 30 (4): 441–5، 2002، doi:10.1038/ng862، PMID 11889467.
- "The paired-like homeodomain protein, Arix, mediates protein kinase A-stimulated dopamine beta-hydroxylase gene transcription through its phosphorylation status"، J. Biol. Chem.، 277 (25): 22915–24، 2002، doi:10.1074/jbc.M201695200، PMID 11943777.
- "The interaction between dHAND and Arix at the dopamine beta-hydroxylase promoter region is independent of direct dHAND binding to DNA"، J. Biol. Chem.، 278 (49): 49652–60، 2003، doi:10.1074/jbc.M308577200، PMID 14506227.
- "Molecular analysis of congenital central hypoventilation syndrome"، Hum. Genet.، 114 (1): 22–6، 2003، doi:10.1007/s00439-003-1036-z، PMID 14566559.
- "A novel PHOX2A/ARIX mutation in an Iranian family with congenital fibrosis of extraocular muscles type 2 (CFEOM2)"، Am. J. Ophthalmol.، 136 (5): 861–5، 2003، doi:10.1016/S0002-9394(03)00891-2، PMID 14597037.
- "ARIX and PHOX2B polymorphisms in patients with congenital superior oblique muscle palsy"، Acta Med. Okayama، 59 (2): 55–62، 2005، PMID 16049556.
- "An in vitro approach to test the possible role of candidate factors in the transcriptional regulation of the RET proto-oncogene"، Gene Expr.، 12 (3): 137–49، 2005، doi:10.3727/000000005783992106، PMID 16127999.
- "ERK1/2 is a negative regulator of homeodomain protein Arix/Phox2a"، J. Neurochem.، 94 (6): 1719–27، 2005، doi:10.1111/j.1471-4159.2005.03333.x، PMID 16156742.
- "Phox2 and dHAND transcription factors select shared and unique target genes in the noradrenergic cell type"، J. Mol. Neurosci.، 27 (3): 281–92، 2005، doi:10.1385/JMN:27:3:281، PMID 16280598.
بوابة علم الأحياء الخلوي والجزيئي
بوابة طب
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