MAML2
MAML2 (Mastermind like transcriptional coactivator 2) هوَ بروتين يُشَفر بواسطة جين MAML2 في الإنسان.[1][2][3]
المراجع
- "Identification of new human mastermind proteins defines a family that consists of positive regulators for notch signaling"، J Biol Chem، 277 (52): 50612–20، ديسمبر 2002، doi:10.1074/jbc.M209529200، PMID 12386158.
- "Entrez Gene: MAML2 mastermind-like 2 (Drosophila)"، مؤرشف من الأصل في 05 ديسمبر 2010.
- "Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors"، Mol Cell Biol، 22 (21): 7688–700، أكتوبر 2002، doi:10.1128/MCB.22.21.7688-7700.2002، PMC 135662، PMID 12370315.
قراءة متعمقة
- "Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."، DNA Res.، 8 (2): 85–95، 2001، doi:10.1093/dnares/8.2.85، PMID 11347906.
- "t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway."، Nat. Genet.، 33 (2): 208–13، 2003، doi:10.1038/ng1083، PMID 12539049.
- "Altered Notch signaling resulting from expression of a WAMTP1-MAML2 gene fusion in mucoepidermoid carcinomas and benign Warthin's tumors."، Exp. Cell Res.، 292 (1): 21–8، 2004، doi:10.1016/j.yexcr.2003.09.007، PMID 14720503.
- "Clear cell hidradenoma of the skin-a third tumor type with a t(11;19)--associated TORC1-MAML2 gene fusion."، Genes Chromosomes Cancer، 43 (2): 202–5، 2005، doi:10.1002/gcc.20168، PMID 15729701.
- "Transforming activity of MECT1-MAML2 fusion oncoprotein is mediated by constitutive CREB activation."، EMBO J.، 24 (13): 2391–402، 2005، doi:10.1038/sj.emboj.7600719، PMC 1173159، PMID 15961999.
- "MECT1-MAML2 fusion transcript defines a favorable subset of mucoepidermoid carcinoma."، Clin. Cancer Res.، 12 (13): 3902–7، 2007، doi:10.1158/1078-0432.CCR-05-2376، PMID 16818685.
- "Frequent fusion of the CRTC1 and MAML2 genes in clear cell variants of cutaneous hidradenomas."، Genes Chromosomes Cancer، 46 (6): 559–63، 2007، doi:10.1002/gcc.20440، PMID 17334997.
- "CRTC1/MAML2 fusion transcript in high grade mucoepidermoid carcinomas of salivary and thyroid glands and Warthin's tumors: implications for histogenesis and biologic behavior."، Genes Chromosomes Cancer، 46 (7): 708–15، 2007، doi:10.1002/gcc.20458، PMID 17437281.
- "Identification of a novel fusion gene MLL-MAML2 in secondary acute myelogenous leukemia and myelodysplastic syndrome with inv(11)(q21q23)."، Genes Chromosomes Cancer، 46 (9): 813–9، 2007، doi:10.1002/gcc.20467، PMID 17551948.
بوابة علم الأحياء الخلوي والجزيئي
بوابة طب
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