MARK2
MARK2 (Microtubule affinity regulating kinase 2) هوَ بروتين يُشَفر بواسطة جين MARK2 في الإنسان.[1][2][3]
الوظيفة
المراجع
- "Entrez Gene: MARK2 MAP/microtubule affinity-regulating kinase 2"، مؤرشف من الأصل في 05 ديسمبر 2010.
- "Human serine/threonine protein kinase EMK1: genomic structure and cDNA cloning of isoforms produced by alternative splicing"، Cytogenet Cell Genet، 81 (3–4): 278–82، أكتوبر 1998، doi:10.1159/000015046، PMID 9730619.
- "Precise localization of D11S1226 to the human EMK1 gene at chromosome band 11q13 by sequence homology search"، Cytogenet Cell Genet، 86 (1): 66–7، أكتوبر 1999، doi:10.1159/000015413، PMID 10516437.
قراءة متعمقة
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- "Identification of 21 novel human protein kinases, including 3 members of a family related to the cell cycle regulator nimA of Aspergillus nidulans"، Cell Growth Differ.، 4 (10): 821–30، 1994، PMID 8274451.
- "Normalization and subtraction: two approaches to facilitate gene discovery"، Genome Res.، 6 (9): 791–806، 1997، doi:10.1101/gr.6.9.791، PMID 8889548.
- "Definition of the minimal MEN1 candidate area based on a 5-Mb integrated map of proximal 11q13. The European Consortium on Men1, (GENEM 1; Groupe d'Etude des Néoplasies Endocriniennes Multiples de type 1)"، Genomics، 37 (3): 354–65، 1997، doi:10.1006/geno.1996.0570، PMID 8938448.
- "MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption"، Cell، 89 (2): 297–308، 1997، doi:10.1016/S0092-8674(00)80208-1، PMID 9108484.
- "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library"، Gene، 200 (1–2): 149–56، 1997، doi:10.1016/S0378-1119(97)00411-3، PMID 9373149.
- "PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling"، Nat. Cell Biol.، 3 (7): 628–36، 2001، doi:10.1038/35083016، PMID 11433294.
- "Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network"، J. Biol. Chem.، 279 (13): 12804–11، 2004، doi:10.1074/jbc.M312171200، PMID 14676191.
- "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway"، Nat. Cell Biol.، 6 (2): 97–105، 2004، doi:10.1038/ncb1086، PMID 14743216.
- "LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1"، EMBO J.، 23 (4): 833–43، 2005، doi:10.1038/sj.emboj.7600110، PMC 381014، PMID 14976552.
- "Splicing alterations in human renal allografts: detection of a new splice variant of protein kinase Par1/Emk1 whose expression is associated with an increase of inflammation in protocol biopsies of transplanted patients"، Biochim. Biophys. Acta، 1689 (1): 58–65، 2004، doi:10.1016/j.bbadis.2004.01.008، PMID 15158914.
- "Large-scale characterization of HeLa cell nuclear phosphoproteins"، Proc. Natl. Acad. Sci. U.S.A.، 101 (33): 12130–5، 2004، doi:10.1073/pnas.0404720101، PMC 514446، PMID 15302935.
- "aPKC acts upstream of PAR-1b in both the establishment and maintenance of mammalian epithelial polarity"، Curr. Biol.، 14 (16): 1425–35، 2004، doi:10.1016/j.cub.2004.08.021، PMID 15324659.
- "Par-1 promotes a hepatic mode of apical protein trafficking in MDCK cells"، Proc. Natl. Acad. Sci. U.S.A.، 101 (38): 13792–7، 2004، doi:10.1073/pnas.0403684101، PMC 518835، PMID 15365179.
- "Up-regulation of Flotillin-2 is associated with melanoma progression and modulates expression of the thrombin receptor protease activated receptor 1"، Cancer Res.، 64 (20): 7361–9، 2004، doi:10.1158/0008-5472.CAN-04-0823، PMID 15492257.
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