SPI1
SPI1 (Spi-1 proto-oncogene) هوَ بروتين يُشَفر بواسطة جين SPI1 في الإنسان.[1]
الوظيفة
المراجع
قراءة متعمقة
- "The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene."، Cell، 61 (1): 113–24، 1990، doi:10.1016/0092-8674(90)90219-5، PMID 2180582.
- "Localization of the human oncogene SPI1 on chromosome 11, region p11.22."، Hum. Genet.، 84 (6): 542–6، 1990، doi:10.1007/bf00210807، PMID 2338340.
- "PU.1 (Spi-1) autoregulates its expression in myeloid cells."، Oncogene، 11 (8): 1549–60، 1995، PMID 7478579.
- "Multiple proteins physically interact with PU.1. Transcriptional synergy with NF-IL6 beta (C/EBP delta, CRP3)."، J. Immunol.، 155 (9): 4330–8، 1995، PMID 7594592.
- "Activating transcription factor 1 and cyclic AMP response element modulator can modulate the activity of the immunoglobulin kappa 3' enhancer."، J. Biol. Chem.، 270 (17): 10304–13، 1995، doi:10.1074/jbc.270.17.10304، PMID 7730336.
- "Hematopoietic lineage- and stage-restricted expression of the ETS oncogene family member PU.1."، Blood، 82 (10): 2998–3004، 1993، PMID 8219191.
- "The activation domain of transcription factor PU.1 binds the retinoblastoma (RB) protein and the transcription factor TFIID in vitro: RB shows sequence similarity to TFIID and TFIIB."، Proc. Natl. Acad. Sci. U.S.A.، 90 (4): 1580–4، 1993، doi:10.1073/pnas.90.4.1580، PMC 45918، PMID 8434021.
- "The transcription factor Spi-1/PU.1 binds RNA and interferes with the RNA-binding protein p54nrb."، J. Biol. Chem.، 271 (19): 11177–81، 1996، doi:10.1074/jbc.271.19.11177، PMID 8626664.
- "Physical interactions between Ets and NF-kappaB/NFAT proteins play an important role in their cooperative activation of the human immunodeficiency virus enhancer in T cells."، J. Virol.، 71 (5): 3563–73، 1997، PMC 191503، PMID 9094628.
- "PU.1 is essential for p47(phox) promoter activity in myeloid cells."، J. Biol. Chem.، 272 (28): 17802–9، 1997، doi:10.1074/jbc.272.28.17802، PMID 9211934.
- "Human T-cell leukemia virus type I Tax transactivates the promoter of human prointerleukin-1beta gene through association with two transcription factors, nuclear factor-interleukin-6 and Spi-1."، Blood، 90 (8): 3142–53، 1997، PMID 9376596.
- "The transcription factor Spi-1/PU.1 interacts with the potential splicing factor TLS."، J. Biol. Chem.، 273 (9): 4838–42، 1998، doi:10.1074/jbc.273.9.4838، PMID 9478924.
- "PU.1 as an essential activator for the expression of gp91(phox) gene in human peripheral neutrophils, monocytes, and B lymphocytes."، Proc. Natl. Acad. Sci. U.S.A.، 95 (11): 6085–90، 1998، doi:10.1073/pnas.95.11.6085، PMC 27589، PMID 9600921.
- "Erg proteins, transcription factors of the Ets family, form homo, heterodimers and ternary complexes via two distinct domains."، Oncogene، 16 (25): 3261–8، 1998، doi:10.1038/sj.onc.1201868، PMID 9681824.
- "Microphthalmia-associated transcription factor interacts with PU.1 and c-Fos: determination of their subcellular localization."، Biochem. Biophys. Res. Commun.، 254 (2): 384–7، 1999، doi:10.1006/bbrc.1998.9918، PMID 9918847.
- "Assembly requirements of PU.1-Pip (IRF-4) activator complexes: inhibiting function in vivo using fused dimers."، EMBO J.، 18 (4): 977–91، 1999، doi:10.1093/emboj/18.4.977، PMC 1171190، PMID 10022840.
- "Physical and functional interactions between the transcription factor PU.1 and the coactivator CBP."، Oncogene، 18 (7): 1495–501، 1999، doi:10.1038/sj.onc.1202427، PMID 10050886.
- "SPI-B activates transcription via a unique proline, serine, and threonine domain and exhibits DNA binding affinity differences from PU.1."، J. Biol. Chem.، 274 (16): 11115–24، 1999، doi:10.1074/jbc.274.16.11115، PMID 10196196.
- "Functional and physical interactions between AML1 proteins and an ETS protein, MEF: implications for the pathogenesis of t(8;21)-positive leukemias."، Mol. Cell. Biol.، 19 (5): 3635–44، 1999، doi:10.1128/mcb.19.5.3635، PMC 84165، PMID 10207087.
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