WNT1
WNT1 (Wnt family member 1) هوَ بروتين يُشَفر بواسطة جين WNT1 في الإنسان.[1][2][3]
المراجع
- "The nucleotide sequence of the human int-1 mammary oncogene; evolutionary conservation of coding and non-coding sequences"، EMBO J، 4 (11): 2905–9، يناير 1986، PMC 554596، PMID 2998762.
- "Chromosome localization of the human oncogene INT1 to 12q13 by in situ hybridization"، Cytogenet Cell Genet، 47 (1–2): 86–87، مايو 1988، doi:10.1159/000132513، PMID 3281802.
- "Entrez Gene: WNT1 wingless-type MMTV integration site family, member 1"، مؤرشف من الأصل في 05 ديسمبر 2010.
قراءة متعمقة
- "int-1--a proto-oncogene involved in cell signalling"، Development، 107 Suppl: 161–7، 1990، PMID 2534596.
- Chance PF؛ Cavalier L؛ Satran D؛ وآخرون (1999)، "Clinical nosologic and genetic aspects of Joubert and related syndromes"، J. Child Neurol.، 14 (10): 660–666، doi:10.1177/088307389901401007، PMID 10511339.
- "The ups and downs of Wnt signaling in prevalent neurological disorders"، Oncogene، 25 (57): 7545–7553، 2007، doi:10.1038/sj.onc.1210064، PMID 17143299.
- "Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development"، Nature، 346 (6287): 847–850، 1990، doi:10.1038/346847a0، PMID 2202907.
- Turc-Carel C؛ Pietrzak E؛ Kakati S؛ وآخرون (1988)، "The human int-1 gene is located at chromosome region 12q12-12q13 and is not rearranged in myxoid liposarcoma with t(12;16) (q13;p11)"، Oncogene Res.، 1 (4): 397–405، PMID 3329717.
- Wang YK؛ Samos CH؛ Peoples R؛ وآخرون (1997)، "A novel human homologue of the Drosophila frizzled wnt receptor gene binds wingless protein and is in the Williams syndrome deletion at 7q11.23"، Hum. Mol. Genet.، 6 (3): 465–472، doi:10.1093/hmg/6.3.465، PMID 9147651.
- Bafico A؛ Gazit A؛ Pramila T؛ وآخرون (1999)، "Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signaling"، J. Biol. Chem.، 274 (23): 16180–16187، doi:10.1074/jbc.274.23.16180، PMID 10347172.
- Gazit A؛ Yaniv A؛ Bafico A؛ وآخرون (1999)، "Human frizzled 1 interacts with transforming Wnts to transduce a TCF dependent transcriptional response"، Oncogene، 18 (44): 5959–5966، doi:10.1038/sj.onc.1202985، PMID 10557084.
- Lee CS؛ Buttitta LA؛ May NR؛ وآخرون (2000)، "SHH-N upregulates Sfrp2 to mediate its competitive interaction with WNT1 and WNT4 in the somitic mesoderm"، Development، 127 (1): 109–18، PMID 10654605.
- Tanaka K؛ Okabayashi K؛ Asashima M؛ وآخرون (2000)، "The evolutionarily conserved porcupine gene family is involved in the processing of the Wnt family"، Eur. J. Biochem.، 267 (13): 4300–4311، doi:10.1046/j.1432-1033.2000.01478.x، PMID 10866835.
- Tamai K؛ Semenov M؛ Kato Y؛ وآخرون (2000)، "LDL-receptor-related proteins in Wnt signal transduction"، Nature، 407 (6803): 530–535، doi:10.1038/35035117، PMID 11029007.
- Mao J؛ Wang J؛ Liu B؛ وآخرون (2001)، "Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway"، Mol. Cell، 7 (4): 801–809، doi:10.1016/S1097-2765(01)00224-6، PMID 11336703.
- "WNT10A and WNT6, clustered in human chromosome 2q35 region with head-to-tail manner, are strongly coexpressed in SW480 cells"، Biochem. Biophys. Res. Commun.، 283 (4): 798–805، 2001، doi:10.1006/bbrc.2001.4855، PMID 11350055.
- Semënov MV؛ Tamai K؛ Brott BK؛ وآخرون (2001)، "Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6"، Curr. Biol.، 11 (12): 951–961، doi:10.1016/S0960-9822(01)00290-1، PMID 11448771.
- Mizushima T؛ Nakagawa H؛ Kamberov YG؛ وآخرون (2002)، "Wnt-1 but not epidermal growth factor induces beta-catenin/T-cell factor-dependent transcription in esophageal cancer cells"، Cancer Res.، 62 (1): 277–82، PMID 11782388.
- Tice DA؛ Szeto W؛ Soloviev I؛ وآخرون (2002)، "Synergistic induction of tumor antigens by Wnt-1 signaling and retinoic acid revealed by gene expression profiling"، J. Biol. Chem.، 277 (16): 14329–14335، doi:10.1074/jbc.M200334200، PMID 11832495.
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