APBA2
APBA2 (Amyloid beta precursor protein binding family A member 2) هوَ بروتين يُشَفر بواسطة جين APBA2 في الإنسان.[1][2]
الوظيفة
المراجع
- "The intracellular cytoplasmic domain of the Alzheimer's disease amyloid precursor protein interacts with phosphotyrosine-binding domain proteins in the yeast two-hybrid system"، FEBS Lett، 397 (2–3): 197–200، يناير 1997، doi:10.1016/S0014-5793(96)01128-3، PMID 8955346.
- "Entrez Gene: APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like)"، مؤرشف من الأصل في 05 ديسمبر 2010.
قراءة متعمقة
- "The PTB domain: a new protein module implicated in signal transduction"، Trends Biochem. Sci.، 20 (7): 277–80، 1995، doi:10.1016/S0968-0004(00)89043-X، PMID 7545337.
- "A "double adaptor" method for improved shotgun library construction"، Anal. Biochem.، 236 (1): 107–13، 1996، doi:10.1006/abio.1996.0138، PMID 8619474.
- "Large-scale concatenation cDNA sequencing"، Genome Res.، 7 (4): 353–8، 1997، doi:10.1101/gr.7.4.353، PMC 139146، PMID 9110174.
- "Mints, Munc18-interacting proteins in synaptic vesicle exocytosis"، J. Biol. Chem.، 272 (50): 31459–64، 1998، doi:10.1074/jbc.272.50.31459، PMID 9395480.
- "Mapping of the human and murine X11-like genes (APBA2 and apba2), the murine Fe65 gene (Apbb1), and the human Fe65-like gene (APBB2): genes encoding phosphotyrosine-binding domain proteins that interact with the Alzheimer's disease amyloid precursor protein"، Mamm. Genome، 9 (6): 473–5، 1998، doi:10.1007/s003359900800، PMID 9585438.
- "The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion"، J. Biol. Chem.، 273 (24): 14761–6، 1998، doi:10.1074/jbc.273.24.14761، PMID 9614075.
- "Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting"، J. Biol. Chem.، 273 (48): 31633–6، 1998، doi:10.1074/jbc.273.48.31633، PMID 9822620.
- "Mint 3: a ubiquitous mint isoform that does not bind to munc18-1 or -2"، Eur. J. Cell Biol.، 77 (3): 161–5، 1999، doi:10.1016/s0171-9335(98)80103-9، PMID 9860131.
- "Interaction of a neuron-specific protein containing PDZ domains with Alzheimer's amyloid precursor protein"، J. Biol. Chem.، 274 (4): 2243–54، 1999، doi:10.1074/jbc.274.4.2243، PMID 9890987.
- "Mint2/X11-like colocalizes with the Alzheimer's disease amyloid precursor protein and is associated with neuritic plaques in Alzheimer's disease"، Eur. J. Neurosci.، 11 (6): 1988–94، 1999، doi:10.1046/j.1460-9568.1999.00610.x، PMID 10336668.
- "PDZ domain-dependent suppression of NF-kappaB/p65-induced Abeta42 production by a neuron-specific X11-like protein"، J. Biol. Chem.، 275 (17): 13056–60، 2000، doi:10.1074/jbc.C000019200، PMID 10777610.
- "Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction"، J. Biol. Chem.، 275 (33): 25616–24، 2000، doi:10.1074/jbc.M000955200، PMID 10827173.
- "Regulation of X11L-dependent amyloid precursor protein metabolism by XB51, a novel X11L-binding protein"، J. Biol. Chem.، 275 (30): 23134–8، 2000، doi:10.1074/jbc.C000302200، PMID 10833507.
- "Mints as adaptors. Direct binding to neurexins and recruitment of munc18"، J. Biol. Chem.، 275 (51): 39803–6، 2001، doi:10.1074/jbc.C000656200، PMID 11036064.
- "X11 alpha and x11 beta interact with presenilin-1 via their PDZ domains"، Mol. Cell. Neurosci.، 16 (5): 557–65، 2001، doi:10.1006/mcne.2000.0898، PMID 11083918.
- "Partial duplication of the APBA2 gene in chromosome 15q13 corresponds to duplicon structures"، BMC Genomics، 4: 15، 2003، doi:10.1186/1471-2164-4-15، PMC 156605، PMID 12720574.
- "XB51 isoforms mediate Alzheimer's beta-amyloid peptide production by X11L (X11-like protein)-dependent and -independent mechanisms"، Biochem. J.، 374 (Pt 1): 261–8، 2003، doi:10.1042/BJ20030489، PMC 1223589، PMID 12780348.
- بوابة علم الأحياء الخلوي والجزيئي
- بوابة الكيمياء الحيوية
- بوابة طب
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