DVL2
DVL2 (Dishevelled segment polarity protein 2) هوَ بروتين يُشَفر بواسطة جين DVL2 في الإنسان.[1][1][2]
الوظيفة
المراجع
- "Entrez Gene: DVL2 dishevelled, dsh homolog 2 (Drosophila)"، مؤرشف من الأصل في 05 ديسمبر 2010.
- "Dishevelled-2 maps to human chromosome 17 and distal to Wnt3a and vestigial tail (vt) on mouse chromosome 11"، Mamm Genome، 7 (6): 475–6، يناير 1997، doi:10.1007/s003359900144، PMID 8662242.
قراءة متعمقة
- "cDNA characterization and chromosomal mapping of two human homologues of the Drosophila dishevelled polarity gene"، Hum. Mol. Genet.، 5 (7): 953–8، 1997، doi:10.1093/hmg/5.7.953، PMID 8817329.
- "Conservation of dishevelled structure and function between flies and mice: isolation and characterization of Dvl2"، Mech. Dev.، 58 (1–2): 15–26، 1997، doi:10.1016/S0925-4773(96)00549-7، PMID 8887313.
- "Human dishevelled genes constitute a DHR-containing multigene family"، Genomics، 42 (2): 302–10، 1997، doi:10.1006/geno.1997.4713، PMID 9192851.
- "Protein phosphatase 2Calpha dephosphorylates axin and activates LEF-1-dependent transcription"، J. Biol. Chem.، 275 (4): 2399–403، 2000، doi:10.1074/jbc.275.4.2399، PMID 10644691.
- "Endogenous protein kinase CK2 participates in Wnt signaling in mammary epithelial cells"، J. Biol. Chem.، 275 (31): 23790–7، 2000، doi:10.1074/jbc.M909107199، PMID 10806215.
- "Dimerization choices control the ability of axin and dishevelled to activate c-Jun N-terminal kinase/stress-activated protein kinase"، J. Biol. Chem.، 275 (32): 25008–14، 2000، doi:10.1074/jbc.M002491200، PMID 10829020.
- "β-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins"، Proc. Natl. Acad. Sci. U.S.A.، 98 (26): 14889–94، 2002، Bibcode:2001PNAS...9814889C، doi:10.1073/pnas.211572798، PMC 64954، PMID 11742073.
- "Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1"، Cell، 107 (7): 843–54، 2002، doi:10.1016/S0092-8674(01)00614-6، PMID 11779461.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences"، Proc. Natl. Acad. Sci. U.S.A.، 99 (26): 16899–903، 2003، Bibcode:2002PNAS...9916899M، doi:10.1073/pnas.242603899، PMC 139241، PMID 12477932.
- "Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation"، Genes Dev.، 17 (2): 295–309، 2003، doi:10.1101/gad.1022203، PMC 195976، PMID 12533515.
- "Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4"، Science، 301 (5638): 1391–4، 2003، Bibcode:2003Sci...301.1391C، doi:10.1126/science.1082808، PMID 12958364.
- "The DIX domain protein coiled-coil-DIX1 inhibits c-Jun N-terminal kinase activation by Axin and dishevelled through distinct mechanisms"، J. Biol. Chem.، 279 (38): 39366–73، 2004، doi:10.1074/jbc.M404598200، PMID 15262978.
- "Independent mutations in mouse Vangl2 that cause neural tube defects in looptail mice impair interaction with members of the Dishevelled family"، J. Biol. Chem.، 279 (50): 52703–13، 2005، doi:10.1074/jbc.M408675200، PMID 15456783.
- "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)"، Genome Res.، 14 (10B): 2121–7، 2004، doi:10.1101/gr.2596504، PMC 528928، PMID 15489334.
- "Towards a proteome-scale map of the human protein-protein interaction network"، Nature، 437 (7062): 1173–8، 2005، Bibcode:2005Natur.437.1173R، doi:10.1038/nature04209، PMID 16189514.
- "Dapper 1 antagonizes Wnt signaling by promoting dishevelled degradation"، J. Biol. Chem.، 281 (13): 8607–12، 2006، doi:10.1074/jbc.M600274200، PMID 16446366.
- "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration"، Cell، 125 (4): 801–14، 2006، doi:10.1016/j.cell.2006.03.032، PMID 16713569.
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