IGF2BP1
IGF2BP1 (Insulin like growth factor 2 mRNA binding protein 1) هوَ بروتين يُشَفر بواسطة جين IGF2BP1 في الإنسان.[1][2][3]
الوظيفة
المراجع
- "A Family of Insulin-Like Growth Factor II mRNA-Binding Proteins Represses Translation in Late Development"، Mol Cell Biol، 19 (2): 1262–70، فبراير 1999، PMC 116055، PMID 9891060.
- "The involvement of a conserved family of RNA binding proteins in embryonic development and carcinogenesis"، Gene، 287 (1–2): 49–54، مايو 2002، doi:10.1016/S0378-1119(01)00866-6، PMID 11992722.
- "Entrez Gene: IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1"، مؤرشف من الأصل في 07 ديسمبر 2019.
قراءة متعمقة
- "Zipcode binding protein 1 regulates the development of dendritic arbors in hippocampal neurons"، J. Neurosci.، 31 (14): 5271–85، 2011، doi:10.1523/JNEUROSCI.2387-10.2011، PMID 21471362.
- Yisraeli JK (2005)، "VICKZ proteins: a multi-talented family of regulatory RNA-binding proteins"، Biol. Cell، 97 (1): 87–96، doi:10.1042/BC20040151، PMID 15601260.
- "Purification and properties of a protein that binds to the C-terminal coding region of human c-myc mRNA"، J. Biol. Chem.، 269 (12): 9261–9، 1994، PMID 8132663.
- Doyle GA؛ Betz NA؛ Leeds PF؛ وآخرون (1999)، "The c-myc coding region determinant-binding protein: a member of a family of KH domain RNA-binding proteins"، Nucleic Acids Res.، 26 (22): 5036–44، doi:10.1093/nar/26.22.5036، PMC 147974، PMID 9801297.
- Runge S؛ Nielsen FC؛ Nielsen J؛ وآخرون (2000)، "H19 RNA binds four molecules of insulin-like growth factor II mRNA-binding protein"، J. Biol. Chem.، 275 (38): 29562–9، doi:10.1074/jbc.M001156200، PMID 10875929.
- Nielsen FC؛ Nielsen J؛ Kristensen MA؛ وآخرون (2003)، "Cytoplasmic trafficking of IGF-II mRNA-binding protein by conserved KH domains"، J. Cell Sci.، 115 (Pt 10): 2087–97، PMID 11973350.
- "Regulation of c-myc mRNA Decay by Translational Pausing in a Coding Region Instability Determinant"، Mol. Cell. Biol.، 22 (12): 3959–69، 2002، doi:10.1128/MCB.22.12.3959-3969.2002، PMC 133878، PMID 12024010.
- Ioannidis P؛ Mahaira L؛ Papadopoulou A؛ وآخرون (2003)، "8q24 Copy number gains and expression of the c-myc mRNA stabilizing protein CRD-BP in primary breast carcinomas"، Int. J. Cancer، 104 (1): 54–9، doi:10.1002/ijc.10794، PMID 12532419.
- Nielsen J؛ Adolph SK؛ Rajpert-De Meyts E؛ وآخرون (2003)، "Nuclear transit of human zipcode-binding protein IMP1"، Biochem. J.، 376 (Pt 2): 383–91، doi:10.1042/BJ20030943، PMC 1223771، PMID 12921532.
- Ota T؛ Suzuki Y؛ Nishikawa T؛ وآخرون (2004)، "Complete sequencing and characterization of 21,243 full-length human cDNAs"، Nat. Genet.، 36 (1): 40–5، doi:10.1038/ng1285، PMID 14702039.
- "Increased expression of IGF II mRNA-binding protein 1 mRNA is associated with an advanced clinical stage and poor prognosis in patients with ovarian cancer"، Int. J. Oncol.، 24 (3): 671–8، 2004، doi:10.3892/ijo.24.3.671، PMID 14767552.
- Hansen TV؛ Hammer NA؛ Nielsen J؛ وآخرون (2004)، "Dwarfism and Impaired Gut Development in Insulin-Like Growth Factor II mRNA-Binding Protein 1-Deficient Mice"، Mol. Cell. Biol.، 24 (10): 4448–64، doi:10.1128/MCB.24.10.4448-4464.2004، PMC 400488، PMID 15121863.
- Ioannidis P؛ Kottaridi C؛ Dimitriadis E؛ وآخرون (2004)، "Expression of the RNA-binding protein CRD-BP in brain and non-small cell lung tumors"، Cancer Lett.، 209 (2): 245–50، doi:10.1016/j.canlet.2003.12.015، PMID 15159028.
- "Visualization of RNA–protein interactions in living cells: FMRP and IMP1 interact on mRNAs"، EMBO J.، 23 (16): 3346–55، 2005، doi:10.1038/sj.emboj.7600341، PMC 514514، PMID 15282548.
- Nielsen J؛ Kristensen MA؛ Willemoës M؛ وآخرون (2004)، "Sequential dimerization of human zipcode-binding protein IMP1 on RNA: a cooperative mechanism providing RNP stability"، Nucleic Acids Res.، 32 (14): 4368–76، doi:10.1093/nar/gkh754، PMC 514376، PMID 15314207.
- Suzuki Y؛ Yamashita R؛ Shirota M؛ وآخرون (2004)، "Sequence Comparison of Human and Mouse Genes Reveals a Homologous Block Structure in the Promoter Regions"، Genome Res.، 14 (9): 1711–8، doi:10.1101/gr.2435604، PMC 515316، PMID 15342556.
- Liao B؛ Patel M؛ Hu Y؛ وآخرون (2005)، "Targeted knockdown of the RNA-binding protein CRD-BP promotes cell proliferation via an insulin-like growth factor II-dependent pathway in human K562 leukemia cells"، J. Biol. Chem.، 279 (47): 48716–24، doi:10.1074/jbc.M405853200، PMID 15355996.
بوابة علم الأحياء الخلوي والجزيئي
بوابة طب
بوابة الكيمياء الحيوية
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.