RAC3

Rac family small GTPase 3
المعرفات
الأسماء المستعارة	RAC3, ras-related C3 botulinum toxin substrate 3, p21-Rac3, ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3), rho family, small GTP binding protein Rac3
معرفات خارجية
أورثولوج
	n/a
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	ويكي بيانات
اعرض/عدّل إنسان

RAC3‏ (Rac family small GTPase 3) هوَ بروتين يُشَفر بواسطة جين RAC3 في الإنسان.[1][1]

المراجع

"Entrez Gene: RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)"، مؤرشف من الأصل في 05 ديسمبر 2010.

قراءة متعمقة

Didsbury J, Weber RF, Bokoch GM, وآخرون (1989)، "rac, a novel ras-related family of proteins that are botulinum toxin substrates."، J. Biol. Chem.، 264 (28): 16378–82، PMID 2674130.
Bonaldo MF, Lennon G, Soares MB (1997)، "Normalization and subtraction: two approaches to facilitate gene discovery."، Genome Res.، 6 (9): 791–806، doi:10.1101/gr.6.9.791، PMID 8889548.
Haataja L, Groffen J, Heisterkamp N (1997)، "Characterization of RAC3, a novel member of the Rho family."، J. Biol. Chem.، 272 (33): 20384–8، doi:10.1074/jbc.272.33.20384، PMID 9252344.
Courjal F, Chuchana P, Theillet C, Fort P (1997)، "Structure and chromosomal assignment to 22q12 and 17qter of the ras-related Rac2 and Rac3 human genes."، Genomics، 44 (2): 242–6، doi:10.1006/geno.1997.4871، PMID 9299243.
Mira JP, Benard V, Groffen J, وآخرون (2000)، "Endogenous, hyperactive Rac3 controls proliferation of breast cancer cells by a p21-activated kinase-dependent pathway"، Proc. Natl. Acad. Sci. U.S.A.، 97 (1): 185–9، Bibcode:2000PNAS...97..185M، doi:10.1073/pnas.97.1.185، PMC 26637، PMID 10618392.
Soutoglou E, Papafotiou G, Katrakili N, Talianidis I (2000)، "Transcriptional activation by hepatocyte nuclear factor-1 requires synergism between multiple coactivator proteins"، J. Biol. Chem.، 275 (17): 12515–20، doi:10.1074/jbc.275.17.12515، PMID 10777539.
Morris CM, Haataja L, McDonald M, وآخرون (2000)، "The small GTPase RAC3 gene is located within chromosome band 17q25.3 outside and telomeric of a region commonly deleted in breast and ovarian tumours"، Cytogenet. Cell Genet.، 89 (1–2): 18–23، doi:10.1159/000015583، PMID 10894930.
Gnanapragasam VJ, Leung HY, Pulimood AS, وآخرون (2002)، "Expression of RAC 3, a steroid hormone receptor co-activator in prostate cancer"، Br. J. Cancer، 85 (12): 1928–36، doi:10.1054/bjoc.2001.2179، PMC 2364015، PMID 11747336.
Haataja L, Kaartinen V, Groffen J, Heisterkamp N (2002)، "The small GTPase Rac3 interacts with the integrin-binding protein CIB and promotes integrin alpha(IIb)beta(3)-mediated adhesion and spreading"، J. Biol. Chem.، 277 (10): 8321–8، doi:10.1074/jbc.M105363200، PMID 11756406.
De Langhe S, Haataja L, Senadheera D, وآخرون (2002)، "Interaction of the small GTPase Rac3 with NRBP, a protein with a kinase-homology domain"، Int. J. Mol. Med.، 9 (5): 451–9، doi:10.3892/ijmm.9.5.451، PMID 11956649.
Strausberg RL, Feingold EA, Grouse LH, وآخرون (2003)، "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences"، Proc. Natl. Acad. Sci. U.S.A.، 99 (26): 16899–903، Bibcode:2002PNAS...9916899M، doi:10.1073/pnas.242603899، PMC 139241، PMID 12477932.
Zhang A, Yeung PL, Li CW, وآخرون (2004)، "Identification of a novel family of ankyrin repeats containing cofactors for p160 nuclear receptor coactivators"، J. Biol. Chem.، 279 (32): 33799–805، doi:10.1074/jbc.M403997200، PMID 15184363.
Gerhard DS, Wagner L, Feingold EA, وآخرون (2004)، "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)"، Genome Res.، 14 (10B): 2121–7، doi:10.1101/gr.2596504، PMC 528928، PMID 15489334.
Hwang SL, Chang JH, Cheng TS, وآخرون (2006)، "Expression of Rac3 in human brain tumors"، Journal of Clinical Neuroscience، 12 (5): 571–4، doi:10.1016/j.jocn.2004.08.013، PMID 15993075.
Chan AY, Coniglio SJ, Chuang YY, وآخرون (2005)، "Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion"، Oncogene، 24 (53): 7821–9، doi:10.1038/sj.onc.1208909، PMID 16027728.
Rual JF, Venkatesan K, Hao T, وآخرون (2005)، "Towards a proteome-scale map of the human protein-protein interaction network"، Nature، 437 (7062): 1173–8، Bibcode:2005Natur.437.1173R، doi:10.1038/nature04209، PMID 16189514.
Baugher PJ, Krishnamoorthy L, Price JE, Dharmawardhane SF (2006)، "Rac1 and Rac3 isoform activation is involved in the invasive and metastatic phenotype of human breast cancer cells"، Breast Cancer Res.، 7 (6): R965–74، doi:10.1186/bcr1329، PMC 1410764، PMID 16280046.
Watabe-Uchida M, John KA, Janas JA, وآخرون (2006)، "The Rac activator DOCK7 regulates neuronal polarity through local phosphorylation of stathmin/Op18"، Neuron، 51 (6): 727–39، doi:10.1016/j.neuron.2006.07.020، PMID 16982419.
Hajdo-Milasinović A, Ellenbroek SI, van Es S, وآخرون (2007)، "Rac1 and Rac3 have opposing functions in cell adhesion and differentiation of neuronal cells"، J. Cell Sci.، 120 (Pt 4): 555–66، doi:10.1242/jcs.03364، PMID 17244648.

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[entrez-1] "Entrez Gene: RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)"، مؤرشف من الأصل في 05 ديسمبر 2010.