MEP1B
MEP1B (Meprin A subunit beta) هوَ بروتين يُشَفر بواسطة جين MEP1B في الإنسان.[1][2]
المراجع
- "Entrez Gene: MEP1B meprin A, beta"، مؤرشف من الأصل في 05 ديسمبر 2010.
- "The structural genes, MEP1A and MEP1B, for the alpha and beta subunits of the metalloendopeptidase meprin map to human chromosomes 6p and 18q, respectively"، Genomics، 25 (1): 300–3، يوليو 1995، doi:10.1016/0888-7543(95)80142-9، PMID 7774936.
قراءة متعمقة
- "Purification of meprin from human kidney and its role in parathyroid hormone degradation."، Biol. Chem. Hoppe-Seyler، 375 (12): 821–4، 1995، PMID 7710697.
- "An old enzyme with a new function: purification and characterization of a distinct matrix-degrading metalloproteinase in rat kidney cortex and its identification as meprin."، J. Cell Biol.، 126 (5): 1319–27، 1994، doi:10.1083/jcb.126.5.1319، PMC 2120165، PMID 8063866.
- "Cloning of the PABA peptide hydrolase alpha subunit (PPH alpha) from human small intestine and its expression in COS-1 cells."، FEBS Lett.، 335 (3): 367–75، 1994، doi:10.1016/0014-5793(93)80421-P، PMID 8262185.
- "Expression and distribution of meprin protease subunits in mouse intestine."، Arch. Biochem. Biophys.، 331 (1): 87–94، 1996، doi:10.1006/abbi.1996.0286، PMID 8660687.
- "Identification of the cysteine residues implicated in the formation of alpha 2 and alpha/beta dimers of rat meprin."، Biochem. J.، 317 (3): 731–8، 1996، PMC 1217546، PMID 8760356.
- "The cleavage of protein kinase A by the kinase-splitting membranal proteinase is reproduced by meprin beta."، J. Biol. Chem.، 271 (47): 30272–80، 1997، doi:10.1074/jbc.271.47.30272، PMID 8939981.
- "Polarised expression of human intestinal N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase (human meprin) alpha and beta subunits in Madin-Darby canine kidney cells."، Eur. J. Biochem.، 247 (3): 920–32، 1997، doi:10.1111/j.1432-1033.1997.00920.x، PMID 9288916.
- "Secretion of human meprin from intestinal epithelial cells depends on differential expression of the alpha and beta subunits."، Eur. J. Biochem.، 259 (1–2): 496–504، 1999، doi:10.1046/j.1432-1327.1999.00071.x، PMID 9914532.
- "Developmental expression of meprin metalloprotease subunits in ICR and C3H/He mouse kidney and intestine in the embryo, postnatally and after weaning."، Biochim. Biophys. Acta، 1518 (1–2): 106–14، 2001، doi:10.1016/S0167-4781(01)00188-9، PMID 11267665.
- "Marked differences between metalloproteases meprin A and B in substrate and peptide bond specificity."، J. Biol. Chem.، 276 (16): 13248–55، 2001، doi:10.1074/jbc.M011414200، PMID 11278902.
- "A selective interaction between OS-9 and the carboxyl-terminal tail of meprin beta."، J. Biol. Chem.، 277 (37): 34413–23، 2002، doi:10.1074/jbc.M203986200، PMID 12093806.
- "Human meprin beta: O-linked glycans in the intervening region of the type I membrane protein protect the C-terminal region from proteolytic cleavage and diminish its secretion."، Biochem. J.، 369 (Pt 3): 659–65، 2003، doi:10.1042/BJ20021398، PMC 1223113، PMID 12387727.
- "Structure of homo- and hetero-oligomeric meprin metalloproteases. Dimers, tetramers, and high molecular mass multimers."، J. Biol. Chem.، 278 (4): 2522–32، 2003، doi:10.1074/jbc.M208808200، PMID 12399461.
- "Targeted disruption of the meprin beta gene in mice leads to underrepresentation of knockout mice and changes in renal gene expression profiles."، Mol. Cell. Biol.، 23 (4): 1221–30، 2003، doi:10.1128/MCB.23.4.1221-1230.2003، PMC 141138، PMID 12556482.
- "Phorbol 12-myristate 13-acetate-induced ectodomain shedding and phosphorylation of the human meprinbeta metalloprotease."، J. Biol. Chem.، 278 (44): 42829–39، 2003، doi:10.1074/jbc.M211169200، PMID 12941954.
- "Generation of biologically active interleukin-1beta by meprin B."، Cytokine، 31 (5): 394–403، 2005، doi:10.1016/j.cyto.2005.06.012، PMID 16095909.
- "The alpha and beta subunits of the metalloprotease meprin are expressed in separate layers of human epidermis, revealing different functions in keratinocyte proliferation and differentiation."، J. Invest. Dermatol.، 127 (5): 1115–25، 2007، doi:10.1038/sj.jid.5700675، PMID 17195012.
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