APLP1
APLP1 (Amyloid beta precursor like protein 1) هوَ بروتين يُشَفر بواسطة جين APLP1 في الإنسان.[1][2][3]
المراجع
- "The amyloid precursor-like protein (APLP) gene maps to the long arm of human chromosome 19"، Genomics، 15 (1): 237–9، يناير 1993، doi:10.1006/geno.1993.1047، PMID 8432545.
- "Identification of the Alzheimer's disease amyloid precursor protein (APP) and its homologue APLP2 as essential modulators of glucose and insulin homeostasis and growth"، J. Pathol.، 215 (2): 155–63، يونيو 2008، doi:10.1002/path.2343، PMID 18393365.
- "Entrez Gene: APLP1 amyloid beta (A4) precursor-like protein 1"، مؤرشف من الأصل في 05 ديسمبر 2010.
قراءة متعمقة
- "It all sticks together--the APP-related family of proteins and Alzheimer's disease."، Mol. Psychiatry، 4 (6): 524–8، 2000، doi:10.1038/sj.mp.4000552، PMID 10578233.
- "Selective localization of amyloid precursor-like protein 1 in the cerebral cortex postsynaptic density."، Brain Res. Mol. Brain Res.، 32 (1): 36–44، 1996، doi:10.1016/0169-328X(95)00328-P، PMID 7494461.
- "The amyloid beta-protein precursor and its mammalian homologues. Evidence for a zinc-modulated heparin-binding superfamily."، J. Biol. Chem.، 269 (43): 26618–21، 1994، PMID 7929392.
- "The amyloid precursor-like protein (APLP) gene maps to the long arm of human chromosome 19."، Genomics، 15 (1): 237–9، 1993، doi:10.1006/geno.1993.1047، PMID 8432545.
- "cDNA cloning and chromosome mapping of the human Fe65 gene: interaction of the conserved cytoplasmic domains of the human beta-amyloid precursor protein and its homologues with the mouse Fe65 protein."، Hum. Mol. Genet.، 5 (10): 1589–98، 1997، doi:10.1093/hmg/5.10.1589، PMID 8894693.
- "Human amyloid precursor-like protein 1--cDNA cloning, ectopic expression in COS-7 cells and identification of soluble forms in the cerebrospinal fluid."، Eur. J. Biochem.، 250 (2): 354–63، 1998، doi:10.1111/j.1432-1033.1997.0354a.x، PMID 9428684.
- "Structure of the human amyloid-precursor-like protein gene APLP1 at 19q13.1."، Hum. Genet.، 102 (2): 192–6، 1998، doi:10.1007/s004390050676، PMID 9521588.
- "Immunohistochemical and in situ analysis of amyloid precursor-like protein-1 and amyloid precursor-like protein-2 expression in Alzheimer disease and aged control brains."، Brain Res.، 804 (1): 45–51، 1998، doi:10.1016/S0006-8993(98)00653-2، PMID 9729270.
- "Interaction of a neuron-specific protein containing PDZ domains with Alzheimer's amyloid precursor protein."، J. Biol. Chem.، 274 (4): 2243–54، 1999، doi:10.1074/jbc.274.4.2243، PMID 9890987.
- "Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1."، J. Neurosci.، 19 (17): 7507–15، 1999، PMID 10460257.
- "Evidence for a copper-binding superfamily of the amyloid precursor protein."، Biochemistry، 41 (30): 9310–20، 2002، doi:10.1021/bi0258647، PMID 12135352.
- "Processing of beta-amyloid precursor-like protein-1 and -2 by gamma-secretase regulates transcription."، J. Biol. Chem.، 277 (46): 44195–201، 2003، doi:10.1074/jbc.M208110200، PMID 12228233.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences."، Proc. Natl. Acad. Sci. U.S.A.، 99 (26): 16899–903، 2003، doi:10.1073/pnas.242603899، PMC 139241، PMID 12477932.
- "gamma-Secretase cleavage and binding to FE65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins."، Biochemistry، 42 (22): 6664–73، 2003، doi:10.1021/bi027375c، PMID 12779321.
- "Tom1, a VHS domain-containing protein, interacts with tollip, ubiquitin, and clathrin."، J. Biol. Chem.، 278 (52): 52865–72، 2004، doi:10.1074/jbc.M306740200، PMID 14563850.
- "Accumulation of the amyloid precursor-like protein APLP2 and reduction of APLP1 in retinoic acid-differentiated human neuroblastoma cells upon curcumin-induced neurite retraction."، Brain Res. Mol. Brain Res.، 119 (1): 62–72، 2004، doi:10.1016/j.molbrainres.2003.08.014، PMID 14597230.
- "Cleavage of amyloid-beta precursor protein and amyloid-beta precursor-like protein by BACE 1."، J. Biol. Chem.، 279 (11): 10542–50، 2004، doi:10.1074/jbc.M310001200، PMID 14699153.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs."، Nat. Genet.، 36 (1): 40–5، 2004، doi:10.1038/ng1285، PMID 14702039.
- "The proteolytic processing of the amyloid precursor protein gene family members APLP-1 and APLP-2 involves alpha-, beta-, gamma-, and epsilon-like cleavages: modulation of APLP-1 processing by n-glycosylation."، J. Biol. Chem.، 279 (18): 18146–56، 2004، doi:10.1074/jbc.M311601200، PMID 14970212.
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