CYP2A13
CYP2A13 (Cytochrome P450 family 2 subfamily A member 13) هوَ بروتين يُشَفر بواسطة جين CYP2A13 في الإنسان.[1][1][2][3]
المراجع
- "Entrez Gene: CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13"، مؤرشف من الأصل في 05 ديسمبر 2010.
- "Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants"، Pharmacogenetics، 14 (1): 1–18، مايو 2004، doi:10.1097/00008571-200401000-00001، PMID 15128046.
- "A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles"، Am J Hum Genet، 57 (3): 651–60، أكتوبر 1995، PMC 1801261، PMID 7668294.
قراءة متعمقة
- "The CYP2A gene subfamily: species differences, regulation, catalytic activities and role in chemical carcinogenesis."، Pharmacogenetics، 5 (Special Issue): S123–8، 1995، doi:10.1097/00008571-199512001-00013، PMID 7581481.
- "Molecular genetics of the human cytochrome P450 monooxygenase superfamily."، Xenobiotica، 28 (12): 1129–65، 1999، doi:10.1080/004982598238868، PMID 9890157.
- "Organization and evolution of the cytochrome P450 CYP2A-2B-2F subfamily gene cluster on human chromosome 19."، J. Mol. Evol.، 41 (6): 894–900، 1996، doi:10.1007/bf00173169، PMID 8587134.
- "Expression of CYP2A genes in human liver and extrahepatic tissues."، Biochem. Pharmacol.، 57 (12): 1407–13، 1999، doi:10.1016/S0006-2952(99)00015-5، PMID 10353262.
- "Human cytochrome P450 CYP2A13: predominant expression in the respiratory tract and its high efficiency metabolic activation of a tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone."، Cancer Res.، 60 (18): 5074–9، 2000، PMID 11016631.
- "Genetic polymorphisms of the human CYP2A13 gene: identification of single-nucleotide polymorphisms and functional characterization of an Arg257Cys variant."، J. Pharmacol. Exp. Ther.، 302 (2): 416–23، 2002، doi:10.1124/jpet.302.2.416، PMID 12130698.
- "Catalog of 680 variations among eight cytochrome p450 ( CYP) genes, nine esterase genes, and two other genes in the Japanese population."، J. Hum. Genet.، 48 (5): 249–70، 2003، doi:10.1007/s10038-003-0021-7، PMID 12721789.
- "Substantial reduction in risk of lung adenocarcinoma associated with genetic polymorphism in CYP2A13, the most active cytochrome P450 for the metabolic activation of tobacco-specific carcinogen NNK."، Cancer Res.، 63 (22): 8057–61، 2004، PMID 14633739.
- "Genetic polymorphism of the human cytochrome CYP2A13 in a French population: implication in lung cancer susceptibility."، Biochem. Biophys. Res. Commun.، 317 (2): 662–9، 2004، doi:10.1016/j.bbrc.2004.03.092، PMID 15063809.
- "Arg257Cys polymorphism of CYP2A13 in a Chinese population."، Clin. Chim. Acta، 343 (1–2): 213–6، 2004، doi:10.1016/j.cccn.2004.01.017، PMID 15115698.
- "Identification of critical amino acid residues of human CYP2A13 for the metabolic activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a tobacco-specific carcinogen"، Drug Metab. Dispos.، 32 (12): 1516–21، 2005، doi:10.1124/dmd.104.001370، PMID 15333516.
- "Eighteen novel polymorphisms of the CYP2A13 gene in Japanese"، Drug Metab. Pharmacokinet.، 18 (1): 86–90، 2005، doi:10.2133/dmpk.18.86، PMID 15618722.
- "Structure of the human lung cytochrome P450 2A13"، J. Biol. Chem.، 282 (23): 17306–13، 2007، doi:10.1074/jbc.M702361200، PMID 17428784.
بوابة علم الأحياء الخلوي والجزيئي
بوابة طب
بوابة الكيمياء الحيوية
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