KHSRP
KHSRP (KH-type splicing regulatory protein) هوَ بروتين يُشَفر بواسطة جين KHSRP في الإنسان.[1][2][3]
الوظيفة
المراجع
- "A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer"، Genes Dev، 11 (8): 1023–36، مايو 1997، doi:10.1101/gad.11.8.1023، PMID 9136930.
- "Entrez Gene: KHSRP KH-type splicing regulatory protein (FUSE binding protein 2)"، مؤرشف من الأصل في 05 ديسمبر 2010.
- "The far upstream element-binding proteins comprise an ancient family of single-strand DNA-binding transactivators"، J Biol Chem، 271 (49): 31679–87، يناير 1997، doi:10.1074/jbc.271.49.31679، PMID 8940189.
قراءة متعمقة
- "Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin."، J. Infect.، 24 (3): 317–20، 1992، doi:10.1016/S0163-4453(05)80037-4، PMID 1602151.
- "Normalization and subtraction: two approaches to facilitate gene discovery."، Genome Res.، 6 (9): 791–806، 1997، doi:10.1101/gr.6.9.791، PMID 8889548.
- "hnRNP H is a component of a splicing enhancer complex that activates a c-src alternative exon in neuronal cells."، Mol. Cell. Biol.، 19 (1): 69–77، 1999، PMC 83866، PMID 9858532.
- "Mapping of the KHSRP gene to a region of conserved synteny on human chromosome 19p13.3 and mouse chromosome 17."، Genomics، 56 (3): 350–2، 1999، doi:10.1006/geno.1998.5725، PMID 10087204.
- "Purification and molecular cloning of a novel essential component of the apolipoprotein B mRNA editing enzyme-complex."، J. Biol. Chem.، 275 (26): 19848–56، 2000، doi:10.1074/jbc.M001786200، PMID 10781591.
- "Multisite RNA binding and release of polypyrimidine tract binding protein during the regulation of c-src neural-specific splicing."، Mol. Cell، 5 (6): 949–57، 2000، doi:10.1016/S1097-2765(00)80260-9، PMID 10911989.
- "Cooperative assembly of an hnRNP complex induced by a tissue-specific homolog of polypyrimidine tract binding protein."، Mol. Cell. Biol.، 20 (20): 7463–79، 2000، doi:10.1128/MCB.20.20.7463-7479.2000، PMC 86300، PMID 11003644.
- "AU binding proteins recruit the exosome to degrade ARE-containing mRNAs."، Cell، 107 (4): 451–64، 2002، doi:10.1016/S0092-8674(01)00578-5، PMID 11719186.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences."، Proc. Natl. Acad. Sci. U.S.A.، 99 (26): 16899–903، 2003، doi:10.1073/pnas.242603899، PMC 139241، PMID 12477932.
- "Differentiation-induced colocalization of the KH-type splicing regulatory protein with polypyrimidine tract binding protein and the c-src pre-mRNA."، Mol. Biol. Cell، 15 (2): 774–86، 2004، doi:10.1091/mbc.E03-09-0692، PMC 329392، PMID 14657238.
- "A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery."، Mol. Cell، 14 (5): 571–83، 2004، doi:10.1016/j.molcel.2004.05.002، PMID 15175153.
- "IL-1beta induces stabilization of IL-8 mRNA in malignant breast cancer cells via the 3' untranslated region: Involvement of divergent RNA-binding factors HuR, KSRP and TIAR."، Int. J. Cancer، 113 (6): 911–9، 2005، doi:10.1002/ijc.20675، PMID 15514971.
- "Beta-amyloid protein converting enzyme 1 and brain-specific type II membrane protein BRI3: binding partners processed by furin."، J. Neurochem.، 92 (1): 93–102، 2005، doi:10.1111/j.1471-4159.2004.02840.x، PMID 15606899.
- "Tethering KSRP, a decay-promoting AU-rich element-binding protein, to mRNAs elicits mRNA decay."، Mol. Cell. Biol.، 26 (10): 3695–706، 2006، doi:10.1128/MCB.26.10.3695-3706.2006، PMC 1489004، PMID 16648466.
- "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."، Nat. Biotechnol.، 24 (10): 1285–92، 2006، doi:10.1038/nbt1240، PMID 16964243.
- "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."، Cell، 127 (3): 635–48، 2006، doi:10.1016/j.cell.2006.09.026، PMID 17081983.
- "The RNA-binding protein KSRP promotes decay of beta-catenin mRNA and is inactivated by PI3K-AKT signaling."، PLoS Biol.، 5 (1): e5، 2007، doi:10.1371/journal.pbio.0050005، PMC 1702562، PMID 17177604.
- "Large-scale mapping of human protein-protein interactions by mass spectrometry."، Mol. Syst. Biol.، 3 (1): 89، 2007، doi:10.1038/msb4100134، PMC 1847948، PMID 17353931.
بوابة الكيمياء الحيوية
بوابة طب
بوابة علم الأحياء الخلوي والجزيئي
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